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The dynamic mechanism of noisy signal decoding in gene regulation

Experimental evidence supports that signaling pathways can induce different dynamics of transcription factor (TF) activation, but how an input signal is encoded by such a dynamic, noisy TF and further decoded by downstream genes remains largely unclear. Here, using a system of stochastic transcripti...

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Detalles Bibliográficos
Autores principales: Liu, Peijiang, Wang, Haohua, Huang, Lifang, Zhou, Tianshou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296728/
https://www.ncbi.nlm.nih.gov/pubmed/28176840
http://dx.doi.org/10.1038/srep42128