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Structural insights into human angiogenin variants implicated in Parkinson’s disease and Amyotrophic Lateral Sclerosis

Mutations in Angiogenin (ANG), a member of the Ribonuclease A superfamily (also known as RNase 5) are known to be associated with Amyotrophic Lateral Sclerosis (ALS, motor neurone disease) (sporadic and familial) and Parkinson’s Disease (PD). In our previous studies we have shown that ANG is express...

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Detalles Bibliográficos
Autores principales: Bradshaw, William J., Rehman, Saima, Pham, Tram T. K., Thiyagarajan, Nethaji, Lee, Rebecca L., Subramanian, Vasanta, Acharya, K. Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296752/
https://www.ncbi.nlm.nih.gov/pubmed/28176817
http://dx.doi.org/10.1038/srep41996