Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis

The ability to suppress host macrophage apoptosis is essential for M. tuberculosis (Mtb) to replicate intracellularly while protecting it from antibiotic treatment. We recently described that Mtb infection upregulated expression of the host phosphatase PPM1A, which impairs the antibacterial response...

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Detalles Bibliográficos
Autores principales: Schaaf, Kaitlyn, Smith, Samuel R., Duverger, Alexandra, Wagner, Frederic, Wolschendorf, Frank, Westfall, Andrew O., Kutsch, Olaf, Sun, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296758/
https://www.ncbi.nlm.nih.gov/pubmed/28176854
http://dx.doi.org/10.1038/srep42101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296758/
https://www.ncbi.nlm.nih.gov/pubmed/28176854
http://dx.doi.org/10.1038/srep42101

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