Structural basis of the interaction between Topoisomerase IIIβ and the TDRD3 auxiliary factor

Topoisomerase IIIβ (TOP3β) is a DNA/RNA topoisomerase that has been implicated in epigenetic or translational control of gene expression. In cells, TOP3β co-exists with its specific auxiliary factor, TDRD3. TDRD3 serves as a scaffold protein to recruit TOP3β to its DNA/RNA substrates accumulating in...

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Detalles Bibliográficos
Autores principales: Goto-Ito, Sakurako, Yamagata, Atsushi, Takahashi, Tomio S., Sato, Yusuke, Fukai, Shuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296760/
https://www.ncbi.nlm.nih.gov/pubmed/28176834
http://dx.doi.org/10.1038/srep42123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296760/
https://www.ncbi.nlm.nih.gov/pubmed/28176834
http://dx.doi.org/10.1038/srep42123

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