Evolution of Shh endoderm enhancers during morphological transition from ventral lungs to dorsal gas bladder

Shh signalling plays a crucial role for endoderm development. A Shh endoderm enhancer, MACS1, is well conserved across terrestrial animals with lungs. Here, we first show that eliminating mouse MACS1 causes severe defects in laryngeal development, indicating that MACS1-directed Shh signalling is ind...

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Detalles Bibliográficos
Autores principales: Sagai, Tomoko, Amano, Takanori, Maeno, Akiteru, Kimura, Tetsuaki, Nakamoto, Masatoshi, Takehana, Yusuke, Naruse, Kiyoshi, Okada, Norihiro, Kiyonari, Hiroshi, Shiroishi, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296767/
https://www.ncbi.nlm.nih.gov/pubmed/28155855
http://dx.doi.org/10.1038/ncomms14300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296767/
https://www.ncbi.nlm.nih.gov/pubmed/28155855
http://dx.doi.org/10.1038/ncomms14300

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