Cargando…

A combinational CRISPR/Cas9 gene-editing approach can halt HIV replication and prevent viral escape

HIV presents one of the highest evolutionary rates ever detected and combination antiretroviral therapy is needed to overcome the plasticity of the virus population and control viral replication. Conventional treatments lack the ability to clear the latent reservoir, which remains the major obstacle...

Descripción completa

Detalles Bibliográficos
Autores principales: Lebbink, Robert Jan, de Jong, Dorien C. M., Wolters, Femke, Kruse, Elisabeth M., van Ham, Petra M., Wiertz, Emmanuel J. H. J., Nijhuis, Monique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296774/
https://www.ncbi.nlm.nih.gov/pubmed/28176813
http://dx.doi.org/10.1038/srep41968