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A combinational CRISPR/Cas9 gene-editing approach can halt HIV replication and prevent viral escape
HIV presents one of the highest evolutionary rates ever detected and combination antiretroviral therapy is needed to overcome the plasticity of the virus population and control viral replication. Conventional treatments lack the ability to clear the latent reservoir, which remains the major obstacle...
Autores principales: | Lebbink, Robert Jan, de Jong, Dorien C. M., Wolters, Femke, Kruse, Elisabeth M., van Ham, Petra M., Wiertz, Emmanuel J. H. J., Nijhuis, Monique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296774/ https://www.ncbi.nlm.nih.gov/pubmed/28176813 http://dx.doi.org/10.1038/srep41968 |
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