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Targeting the molecular chaperone SlyD to inhibit bacterial growth with a small molecule

Molecular chaperones are essential molecules for cell growth, whereby they maintain protein homeostasis. Because of their central cellular function, bacterial chaperones might be potential candidates for drug targets. Antimicrobial resistance is currently one of the greatest threats to human health,...

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Detalles Bibliográficos
Autores principales: Kumar, Amit, Balbach, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296862/
https://www.ncbi.nlm.nih.gov/pubmed/28176839
http://dx.doi.org/10.1038/srep42141