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A versatile assay to determine bacterial and host factors contributing to opsonophagocytotic killing in hirudin-anticoagulated whole blood

Most bacteria entering the bloodstream will be eliminated through complement activation on the bacterial surface and opsonophagocytosis. However, when these protective innate immune systems do not work optimally, or when bacteria are equipped with immune evasion mechanisms that prevent killing, this...

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Detalles Bibliográficos
Autores principales: van der Maten, Erika, de Jonge, Marien I., de Groot, Ronald, van der Flier, Michiel, Langereis, Jeroen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296863/
https://www.ncbi.nlm.nih.gov/pubmed/28176849
http://dx.doi.org/10.1038/srep42137