Susceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection

BACKGROUND: The endoplasmic reticulum enzyme glucose-6-phosphatase catalyzes the common terminal reaction in the gluconeogenic/glycogenolytic pathways and plays a central role in glucose homeostasis. In most mammals, different G6PC subunits are encoded by three paralogous genes (G6PC, G6PC2, and G6P...

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Detalles Bibliográficos
Autores principales: Al-Daghri, Nasser M., Pontremoli, Chiara, Cagliani, Rachele, Forni, Diego, Alokail, Majed S., Al-Attas, Omar S., Sabico, Shaun, Riva, Stefania, Clerici, Mario, Sironi, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297017/
https://www.ncbi.nlm.nih.gov/pubmed/28173748
http://dx.doi.org/10.1186/s12862-017-0897-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297017/
https://www.ncbi.nlm.nih.gov/pubmed/28173748
http://dx.doi.org/10.1186/s12862-017-0897-z

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