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Susceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection

BACKGROUND: The endoplasmic reticulum enzyme glucose-6-phosphatase catalyzes the common terminal reaction in the gluconeogenic/glycogenolytic pathways and plays a central role in glucose homeostasis. In most mammals, different G6PC subunits are encoded by three paralogous genes (G6PC, G6PC2, and G6P...

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Detalles Bibliográficos
Autores principales:	Al-Daghri, Nasser M., Pontremoli, Chiara, Cagliani, Rachele, Forni, Diego, Alokail, Majed S., Al-Attas, Omar S., Sabico, Shaun, Riva, Stefania, Clerici, Mario, Sironi, Manuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297017/ https://www.ncbi.nlm.nih.gov/pubmed/28173748 http://dx.doi.org/10.1186/s12862-017-0897-z

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