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Melanoma genome evolution across species

BACKGROUND: Cancer genomes evolve in both space and time, which contributes to the genetic heterogeneity that underlies tumor progression and drug resistance. In human melanoma, identifying mechanistically important events in tumor evolution is hampered due to the high background mutation rate from...

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Detalles Bibliográficos
Autores principales: Kansler, Emily R., Verma, Akanksha, Langdon, Erin M., Simon-Vermot, Theresa, Yin, Alexandra, Lee, William, Attiyeh, Marc, Elemento, Olivier, White, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297047/
https://www.ncbi.nlm.nih.gov/pubmed/28173755
http://dx.doi.org/10.1186/s12864-017-3518-8