Oxidized LDL-induced JAB1 influences NF-κB independent inflammatory signaling in human macrophages during foam cell formation

BACKGROUND: Oxidized low-density lipoprotein (oxLDL) mediates the transformation of macrophages (MΦ) to cholesterol-rich foam cells and the release of pro-inflammatory cytokines during atherogenesis. JAB1 (Jun activation domain binding protein-1) is present in all stages of human plaques, involved i...

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Detalles Bibliográficos
Autores principales: Schwarz, Anja, Bonaterra, Gabriel A., Schwarzbach, Hans, Kinscherf, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297127/
https://www.ncbi.nlm.nih.gov/pubmed/28173800
http://dx.doi.org/10.1186/s12929-017-0320-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297127/
https://www.ncbi.nlm.nih.gov/pubmed/28173800
http://dx.doi.org/10.1186/s12929-017-0320-5

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