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Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in mice
BACKGROUND: Alzheimer’s disease (AD) is characterized by progressive cognitive decline and memory loss. Environmental factors and gene-environment interactions (GXE) may increase AD risk, accelerate cognitive decline, and impair learning and memory. However, there is currently little direct evidence...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297175/ https://www.ncbi.nlm.nih.gov/pubmed/28173832 http://dx.doi.org/10.1186/s13024-017-0155-2 |