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Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in mice

BACKGROUND: Alzheimer’s disease (AD) is characterized by progressive cognitive decline and memory loss. Environmental factors and gene-environment interactions (GXE) may increase AD risk, accelerate cognitive decline, and impair learning and memory. However, there is currently little direct evidence...

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Detalles Bibliográficos
Autores principales:	Engstrom, Anna K., Snyder, Jessica M., Maeda, Nobuyo, Xia, Zhengui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297175/ https://www.ncbi.nlm.nih.gov/pubmed/28173832 http://dx.doi.org/10.1186/s13024-017-0155-2

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