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Potential importance of protease activated receptor (PAR)-1 expression in the tumor stroma of non-small-cell lung cancer

BACKGROUND: Protease activated receptor (PAR)-1 expression is increased in a variety of tumor cells. In preclinical models, tumor cell PAR-1 appeared to be involved in the regulation of lung tumor growth and metastasis; however the role of PAR-1 in the lung tumor microenvironment, which is emerging...

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Detalles Bibliográficos
Autores principales: Lin, Cong, Majoor, Christof J., Roelofs, Joris J. T. H., de Kruif, Martijn D., Horlings, Hugo M., Borensztajn, Keren, Spek, C. Arnold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297223/
https://www.ncbi.nlm.nih.gov/pubmed/28173772
http://dx.doi.org/10.1186/s12885-017-3081-3