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A critical role of platelet TGF-β release in podoplanin-mediated tumour invasion and metastasis

The tumour microenvironment is critical for various characteristics of tumour malignancies. Platelets, as part of the tumour microenvironment, are associated with metastasis formation via increasing the rate of tumour embolus formation in microvasculature. However, the mechanisms underlying the abil...

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Detalles Bibliográficos
Autores principales: Takemoto, Ai, Okitaka, Mina, Takagi, Satoshi, Takami, Miho, Sato, Shigeo, Nishio, Makoto, Okumura, Sakae, Fujita, Naoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297242/
https://www.ncbi.nlm.nih.gov/pubmed/28176852
http://dx.doi.org/10.1038/srep42186