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A critical role of platelet TGF-β release in podoplanin-mediated tumour invasion and metastasis
The tumour microenvironment is critical for various characteristics of tumour malignancies. Platelets, as part of the tumour microenvironment, are associated with metastasis formation via increasing the rate of tumour embolus formation in microvasculature. However, the mechanisms underlying the abil...
Autores principales: | Takemoto, Ai, Okitaka, Mina, Takagi, Satoshi, Takami, Miho, Sato, Shigeo, Nishio, Makoto, Okumura, Sakae, Fujita, Naoya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297242/ https://www.ncbi.nlm.nih.gov/pubmed/28176852 http://dx.doi.org/10.1038/srep42186 |
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