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Inhibition of Hydrogen Peroxide-Induced Human Umbilical Vein Endothelial Cells Aging by Allicin Depends on Sirtuin1 Activation

BACKGROUND: The abnormal activity of Sirtuin 1 (Sirt1) is closely related to the aging of vascular endothelial cells. As a bioactive molecule, allicin has antioxidant, anti-inflammatory, and lipid-regulating mechanisms. However, few reports about the relationship of allicin and Sirt1 have been publi...

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Detalles Bibliográficos
Autores principales: Lin, Xiao-Long, Liu, Yuanbo, Liu, Mihua, Hu, Huijun, Pan, Yongquan, Fan, Xiao-Juan, Hu, Xue-Mei, Zou, Wei-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297325/
https://www.ncbi.nlm.nih.gov/pubmed/28139552
http://dx.doi.org/10.12659/MSM.899730