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CHARMM Force Field Parameterization of Peroxisome Proliferator-Activated Receptor γ Ligands
The peroxisome proliferator-activated receptor γ (PPARγ) ligands are important therapeutic drugs for the treatment of type 2 diabetes, obesity and cardiovascular diseases. In particular, partial agonists and non-agonists are interesting targets to reduce glucose levels, presenting few side effects i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297650/ https://www.ncbi.nlm.nih.gov/pubmed/28025495 http://dx.doi.org/10.3390/ijms18010015 |