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Tumor-Derived Tissue Factor Aberrantly Activates Complement and Facilitates Lung Tumor Progression via Recruitment of Myeloid-Derived Suppressor Cells

The initiator of extrinsic coagulation, tissue factor (TF), and its non-coagulant isoform alternatively spliced TF (asTF) are closely associated with tumor development. In the tumor microenvironment, the role of TF-induced coagulation in tumor progression remains to be fully elucidated. Using TF-kno...

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Detalles Bibliográficos
Autores principales: Han, Xiao, Zha, Haoran, Yang, Fei, Guo, Bo, Zhu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297657/
https://www.ncbi.nlm.nih.gov/pubmed/28106852
http://dx.doi.org/10.3390/ijms18010022