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Mobilization of Nuclear Copper by Green Tea Polyphenol Epicatechin-3-Gallate and Subsequent Prooxidant Breakage of Cellular DNA: Implications for Cancer Chemotherapy

Epidemiological as well as experimental evidence exists in support of chemopreventive and anticancer properties of green tea and its constituents. The gallocatechin, epicatechin-3-gallate is a major polyphenol present in green tea, shown responsible for these effects. Plant-derived polyphenolic comp...

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Detalles Bibliográficos
Autores principales: Farhan, Mohd, Oves, Mohammad, Chibber, Sandesh, Hadi, Sheikh Mumtaz, Ahmad, Aamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297669/
https://www.ncbi.nlm.nih.gov/pubmed/28035959
http://dx.doi.org/10.3390/ijms18010034