A Systems Biological View of Life-and-Death Decision with Respect to Endoplasmic Reticulum Stress—The Role of PERK Pathway

Accumulation of misfolded/unfolded proteins in the endoplasmic reticulum (ER) leads to the activation of three branches (Protein kinase (RNA)-like endoplasmic reticulum kinase [PERK], Inositol requiring protein 1 [IRE-1] and Activating trascription factor 6 [ATF6], respectively) of unfolded protein...

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Detalles Bibliográficos
Autores principales: Márton, Margita, Kurucz, Anita, Lizák, Beáta, Margittai, Éva, Bánhegyi, Gábor, Kapuy, Orsolya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297693/
https://www.ncbi.nlm.nih.gov/pubmed/28067773
http://dx.doi.org/10.3390/ijms18010058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297693/
https://www.ncbi.nlm.nih.gov/pubmed/28067773
http://dx.doi.org/10.3390/ijms18010058

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