Targeting IRES-Mediated p53 Synthesis for Cancer Diagnosis and Therapeutics

While translational regulation of p53 by the internal ribosome entry site (IRES) at its 5′-untranslated region following DNA damage has been widely accepted, the detailed mechanism underlying the translational control of p53 by its IRES sequence is still poorly understood. In this review, we will fo...

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Detalles Bibliográficos
Autores principales: Ji, Bai, Harris, Benjamin R. E., Liu, Yahui, Deng, Yibin, Gradilone, Sergio A., Cleary, Margot P., Liu, Jianhua, Yang, Da-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297727/
https://www.ncbi.nlm.nih.gov/pubmed/28054974
http://dx.doi.org/10.3390/ijms18010093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297727/
https://www.ncbi.nlm.nih.gov/pubmed/28054974
http://dx.doi.org/10.3390/ijms18010093

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