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Targeting IRES-Mediated p53 Synthesis for Cancer Diagnosis and Therapeutics
While translational regulation of p53 by the internal ribosome entry site (IRES) at its 5′-untranslated region following DNA damage has been widely accepted, the detailed mechanism underlying the translational control of p53 by its IRES sequence is still poorly understood. In this review, we will fo...
Autores principales: | Ji, Bai, Harris, Benjamin R. E., Liu, Yahui, Deng, Yibin, Gradilone, Sergio A., Cleary, Margot P., Liu, Jianhua, Yang, Da-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297727/ https://www.ncbi.nlm.nih.gov/pubmed/28054974 http://dx.doi.org/10.3390/ijms18010093 |
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