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Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/β-Catenin Pathway

Mechanical loading and hydrostatic pressure (HP) regulate chondrocytes’ metabolism; however, how mechanical stimulation acts remain unclear. MicroRNAs (miRNAs) play an important role in cartilage homeostasis, mechanotransduction, and in the pathogenesis of osteoarthritis (OA). This study investigate...

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Detalles Bibliográficos
Autores principales: Cheleschi, Sara, De Palma, Anna, Pecorelli, Alessandra, Pascarelli, Nicola Antonio, Valacchi, Giuseppe, Belmonte, Giuseppe, Carta, Serafino, Galeazzi, Mauro, Fioravanti, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297766/
https://www.ncbi.nlm.nih.gov/pubmed/28085114
http://dx.doi.org/10.3390/ijms18010133