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A Thoroughly Validated Virtual Screening Strategy for Discovery of Novel HDAC3 Inhibitors

Histone deacetylase 3 (HDAC3) has been recently identified as a potential target for the treatment of cancer and other diseases, such as chronic inflammation, neurodegenerative diseases, and diabetes. Virtual screening (VS) is currently a routine technique for hit identification, but its success dep...

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Detalles Bibliográficos
Autores principales: Hu, Huabin, Xia, Jie, Wang, Dongmei, Wang, Xiang Simon, Wu, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297770/
https://www.ncbi.nlm.nih.gov/pubmed/28106794
http://dx.doi.org/10.3390/ijms18010137