Mutation-Structure-Function Relationship Based Integrated Strategy Reveals the Potential Impact of Deleterious Missense Mutations in Autophagy Related Proteins on Hepatocellular Carcinoma (HCC): A Comprehensive Informatics Approach

Autophagy, an evolutionary conserved multifaceted lysosome-mediated bulk degradation system, plays a vital role in liver pathologies including hepatocellular carcinoma (HCC). Post-translational modifications (PTMs) and genetic variations in autophagy components have emerged as significant determinan...

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Detalles Bibliográficos
Autores principales: Awan, Faryal Mehwish, Obaid, Ayesha, Ikram, Aqsa, Janjua, Hussnain Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297772/
https://www.ncbi.nlm.nih.gov/pubmed/28085066
http://dx.doi.org/10.3390/ijms18010139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297772/
https://www.ncbi.nlm.nih.gov/pubmed/28085066
http://dx.doi.org/10.3390/ijms18010139

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