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A Novel Combination RNAi toward Warburg Effect by Replacement with miR-145 and Silencing of PTBP1 Induces Apoptotic Cell Death in Bladder Cancer Cells

Bladder cancer is one of the most difficult malignancies to control. We explored the use of a novel RNA-interference method for a driver oncogene regulating cancer specific energy metabolism by the combination treatment with a small interfering RNA (siRNA) and a microRNA. After transfection of T24 a...

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Detalles Bibliográficos
Autores principales: Takai, Tomoaki, Yoshikawa, Yuki, Inamoto, Teruo, Minami, Koichiro, Taniguchi, Kohei, Sugito, Nobuhiko, Kuranaga, Yuki, Shinohara, Haruka, Kumazaki, Minami, Tsujino, Takuya, Takahara, Kiyoshi, Ito, Yuko, Akao, Yukihiro, Azuma, Haruhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297811/
https://www.ncbi.nlm.nih.gov/pubmed/28106737
http://dx.doi.org/10.3390/ijms18010179