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MicroRNA-29a Alleviates Bile Duct Ligation Exacerbation of Hepatic Fibrosis in Mice through Epigenetic Control of Methyltransferases

MicroRNA-29 (miR-29) is found to modulate hepatic stellate cells’ (HSCs) activation and, thereby, reduces liver fibrosis pathogenesis. Histone methyltransferase regulation of epigenetic reactions reportedly participates in hepatic fibrosis. This study is undertaken to investigate the miR-29a regulat...

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Detalles Bibliográficos
Autores principales: Yang, Ya-Ling, Wang, Feng-Sheng, Li, Sung-Chou, Tiao, Mao-Meng, Huang, Ying-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297823/
https://www.ncbi.nlm.nih.gov/pubmed/28106784
http://dx.doi.org/10.3390/ijms18010192