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Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer

Cancer cells generally rely on aerobic glycolysis as a major source of energy. Methylglyoxal (MG), a dicarbonyl compound that is produced as a side product during glycolysis, is highly reactive and induces the formation of advanced glycation end-products that are implicated in several pathologies in...

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Detalles Bibliográficos
Autores principales: Chiavarina, Barbara, Nokin, Marie-Julie, Bellier, Justine, Durieux, Florence, Bletard, Noëlla, Sherer, Félicie, Lovinfosse, Pierre, Peulen, Olivier, Verset, Laurine, Dehon, Romain, Demetter, Pieter, Turtoi, Andrei, Uchida, Koji, Goldman, Serge, Hustinx, Roland, Delvenne, Philippe, Castronovo, Vincent, Bellahcène, Akeila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297842/
https://www.ncbi.nlm.nih.gov/pubmed/28117708
http://dx.doi.org/10.3390/ijms18010213