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Decreased Sp1 Expression Mediates Downregulation of SHIP2 in Gastric Cancer Cells

Past studies have shown that the Src homology 2-containing inositol 5-phosphatase 2 (SHIP2) is commonly downregulated in gastric cancer, which contributes to elevated activation of PI3K/Akt signaling, proliferation and tumorigenesis of gastric cancer cells. However, the mechanisms underlying the red...

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Detalles Bibliográficos
Autores principales: Ye, Yan, Qian, Xue Yi, Xiao, Miao Miao, Shao, Yu Ling, Guo, Li Mei, Liao, Dong Ping, Da, Jie, Zhang, Lin Jie, Xu, Jiegou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297849/
https://www.ncbi.nlm.nih.gov/pubmed/28117748
http://dx.doi.org/10.3390/ijms18010220