Molecular Basis for the Neutralization of Tumor Necrosis Factor α by Certolizumab Pegol in the Treatment of Inflammatory Autoimmune Diseases

Monoclonal antibodies against TNFα, including infliximab, adalimumab, golimumab, and certolizumab pegol, are widely used for the treatment of the inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease. Recently, the crystal structures of TNFα, in complex with the Fab fragm...

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Detalles Bibliográficos
Autores principales: Lee, Jee Un, Shin, Woori, Son, Ji Young, Yoo, Ki-Young, Heo, Yong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297857/
https://www.ncbi.nlm.nih.gov/pubmed/28124979
http://dx.doi.org/10.3390/ijms18010228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297857/
https://www.ncbi.nlm.nih.gov/pubmed/28124979
http://dx.doi.org/10.3390/ijms18010228

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