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Pharmacokinetic Interaction Between Isavuconazole and a Fixed‐Dose Combination of Lopinavir 400 mg/Ritonavir 100 mg in Healthy Subjects

This phase 1, open‐label study evaluated the pharmacokinetic effects of coadministration of the antifungal agent, isavuconazole (administered as its water‐soluble prodrug isavuconazonium sulfate), with the antiretroviral agent lopinavir/ritonavir in healthy adults. In part 1, 13 subjects were random...

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Detalles Bibliográficos
Autores principales: Yamazaki, Takao, Desai, Amit, Han, David, Kato, Kota, Kowalski, Donna, Akhtar, Shahzad, Lademacher, Christopher, Kovanda, Laura, Townsend, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297880/
https://www.ncbi.nlm.nih.gov/pubmed/27273248
http://dx.doi.org/10.1002/cpdd.282