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A Regulatory Network Involving β‐Catenin, e‐Cadherin, PI3k/Akt, and Slug Balances Self‐Renewal and Differentiation of Human Pluripotent Stem Cells In Response to Wnt Signaling

The mechanisms underlying disparate roles of the canonical Wnt signaling pathway in maintaining self‐renewal or inducing differentiation and lineage specification in embryonic stem cells (ESCs) are not clear. In this study, we provide the first demonstration that self‐renewal versus differentiation...

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Detalles Bibliográficos
Autores principales: Huang, Tyng‐Shyan, Li, Li, Moalim‐Nour, Lilian, Jia, Deyong, Bai, Jian, Yao, Zemin, Bennett, Steffany A. L., Figeys, Daniel, Wang, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297972/
https://www.ncbi.nlm.nih.gov/pubmed/25538040
http://dx.doi.org/10.1002/stem.1944