Multiple rare genetic variants co‐segregating with familial IgA nephropathy all act within a single immune‐related network

BACKGROUND: IgA nephropathy (IgAN) is a common complex disease with a strong genetic involvement. We aimed to identify novel, rare, highly penetrant risk variants combining family‐based linkage analysis with whole‐exome sequencing (WES). METHODS: Linkage analysis of 16 kindreds of South Italian ance...

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Detalles Bibliográficos
Autores principales: Cox, S. N., Pesce, F., El‐Sayed Moustafa, J.S., Sallustio, F., Serino, G., Kkoufou, C., Giampetruzzi, A., Ancona, N., Falchi, M., Schena, F. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297991/
https://www.ncbi.nlm.nih.gov/pubmed/27730700
http://dx.doi.org/10.1111/joim.12565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297991/
https://www.ncbi.nlm.nih.gov/pubmed/27730700
http://dx.doi.org/10.1111/joim.12565

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