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Multiple rare genetic variants co‐segregating with familial IgA nephropathy all act within a single immune‐related network
BACKGROUND: IgA nephropathy (IgAN) is a common complex disease with a strong genetic involvement. We aimed to identify novel, rare, highly penetrant risk variants combining family‐based linkage analysis with whole‐exome sequencing (WES). METHODS: Linkage analysis of 16 kindreds of South Italian ance...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297991/ https://www.ncbi.nlm.nih.gov/pubmed/27730700 http://dx.doi.org/10.1111/joim.12565 |