Pharmacokinetic and Pharmacodynamic Evaluation of the Drug‐Drug Interaction Between Isavuconazole and Warfarin in Healthy Subjects

This phase 1 trial evaluated pharmacokinetic and pharmacodynamic interactions between the novel triazole antifungal agent isavuconazole and warfarin in healthy adults. Multiple doses of isavuconazole were administered as the oral prodrug, isavuconazonium sulfate (372 mg 3 times a day for 2 days load...

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Detalles Bibliográficos
Autores principales: Desai, Amit, Yamazaki, Takao, Dietz, Albert J., Kowalski, Donna, Lademacher, Christopher, Pearlman, Helene, Akhtar, Shahzad, Townsend, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298089/
https://www.ncbi.nlm.nih.gov/pubmed/27278712
http://dx.doi.org/10.1002/cpdd.283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298089/
https://www.ncbi.nlm.nih.gov/pubmed/27278712
http://dx.doi.org/10.1002/cpdd.283

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