The 2.0 Å X-ray structure for yeast acetohydroxyacid synthase provides new insights into its cofactor and quaternary structure requirements

Acetohydroxyacid synthase (AHAS) catalyzes the first step of branched-chain amino acid biosynthesis, a pathway essential to the life-cycle of plants and micro-organisms. The catalytic subunit has thiamin diphosphate (ThDP) and flavin adenine dinucleotide (FAD) as indispensable co-factors. A new, hig...

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Detalles Bibliográficos
Autores principales: Lonhienne, Thierry, Garcia, Mario D., Fraser, James A., Williams, Craig M., Guddat, Luke W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298238/
https://www.ncbi.nlm.nih.gov/pubmed/28178302
http://dx.doi.org/10.1371/journal.pone.0171443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298238/
https://www.ncbi.nlm.nih.gov/pubmed/28178302
http://dx.doi.org/10.1371/journal.pone.0171443

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