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Synthetic lethal mutations in the cyclin A interface of human cytomegalovirus
Generally, the antagonism between host restriction factors and viral countermeasures decides on cellular permissiveness or resistance to virus infection. Human cytomegalovirus (HCMV) has evolved an additional level of self-imposed restriction by the viral tegument protein pp150. Depending on a cycli...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298330/ https://www.ncbi.nlm.nih.gov/pubmed/28129404 http://dx.doi.org/10.1371/journal.ppat.1006193 |