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A Legionella Effector Disrupts Host Cytoskeletal Structure by Cleaving Actin

Legionella pneumophila, the etiological agent of Legionnaires’ disease, replicates intracellularly in protozoan and human hosts. Successful colonization and replication of this pathogen in host cells requires the Dot/Icm type IVB secretion system, which translocates approximately 300 effector protei...

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Detalles Bibliográficos
Autores principales: Liu, Yao, Zhu, Wenhan, Tan, Yunhao, Nakayasu, Ernesto S., Staiger, Christopher J., Luo, Zhao-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298343/
https://www.ncbi.nlm.nih.gov/pubmed/28129393
http://dx.doi.org/10.1371/journal.ppat.1006186