Genetic defects in β-spectrin and tau sensitize C. elegans axons to movement-induced damage via torque-tension coupling

Our bodies are in constant motion and so are the neurons that invade each tissue. Motion-induced neuron deformation and damage are associated with several neurodegenerative conditions. Here, we investigated the question of how the neuronal cytoskeleton protects axons and dendrites from mechanical st...

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Detalles Bibliográficos
Autores principales: Krieg, Michael, Stühmer, Jan, Cueva, Juan G, Fetter, Richard, Spilker, Kerri, Cremers, Daniel, Shen, Kang, Dunn, Alexander R, Goodman, Miriam B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298879/
https://www.ncbi.nlm.nih.gov/pubmed/28098556
http://dx.doi.org/10.7554/eLife.20172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298879/
https://www.ncbi.nlm.nih.gov/pubmed/28098556
http://dx.doi.org/10.7554/eLife.20172

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