Cargando…
Genetic defects in β-spectrin and tau sensitize C. elegans axons to movement-induced damage via torque-tension coupling
Our bodies are in constant motion and so are the neurons that invade each tissue. Motion-induced neuron deformation and damage are associated with several neurodegenerative conditions. Here, we investigated the question of how the neuronal cytoskeleton protects axons and dendrites from mechanical st...
Autores principales: | Krieg, Michael, Stühmer, Jan, Cueva, Juan G, Fetter, Richard, Spilker, Kerri, Cremers, Daniel, Shen, Kang, Dunn, Alexander R, Goodman, Miriam B |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298879/ https://www.ncbi.nlm.nih.gov/pubmed/28098556 http://dx.doi.org/10.7554/eLife.20172 |
Ejemplares similares
-
Mechanical Control of the Sense of Touch by β Spectrin
por: Krieg, Michael, et al.
Publicado: (2014) -
The axonal actin-spectrin lattice acts as a tension buffering shock absorber
por: Dubey, Sushil, et al.
Publicado: (2020) -
PTRN-1, a microtubule minus end-binding CAMSAP homolog, promotes microtubule function in Caenorhabditis elegans neurons
por: Richardson, Claire E, et al.
Publicado: (2014) -
Axonal spectrins: All-purpose fences
por: Eshed-Eisenbach, Yael, et al.
Publicado: (2013) -
Muscle and epidermal contributions of the structural protein β-spectrin promote hypergravity-induced motor neuron axon defects in C. elegans
por: Kalichamy, Saraswathi S., et al.
Publicado: (2020)