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My Cousin, My Enemy: quasispecies suppression of drug resistance
If a freshly minted genome contains a mutation that confers drug resistance, will it be selected in the presence of the drug? Not necessarily. During viral infections, newly synthesized viral genomes occupy the same cells as parent and other progeny genomes. If the antiviral target is chosen so that...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298929/ https://www.ncbi.nlm.nih.gov/pubmed/27764731 http://dx.doi.org/10.1016/j.coviro.2016.09.011 |