Cargando…

My Cousin, My Enemy: quasispecies suppression of drug resistance

If a freshly minted genome contains a mutation that confers drug resistance, will it be selected in the presence of the drug? Not necessarily. During viral infections, newly synthesized viral genomes occupy the same cells as parent and other progeny genomes. If the antiviral target is chosen so that...

Descripción completa

Detalles Bibliográficos
Autores principales: Kirkegaard, Karla, van Buuren, Nicholas J, Mateo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298929/
https://www.ncbi.nlm.nih.gov/pubmed/27764731
http://dx.doi.org/10.1016/j.coviro.2016.09.011