Cargando…

NF-κB regulates neuronal ankyrin-G via a negative feedback loop

The axon initial segment (AIS) is a neuronal compartment defined by ankyrin-G expression. We here demonstrate that the IKK-complex co-localizes and interacts with the cytoskeletal anchor protein ankyrin-G in immunoprecipitation and proximity-ligation experiments in cortical neurons. Overexpression o...

Descripción completa

Detalles Bibliográficos
Autores principales:	König, Hans-Georg, Schwamborn, Robert, Andresen, Silke, Kinsella, Sinéad, Watters, Orla, Fenner, Beau, Prehn, Jochen H. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299403/ https://www.ncbi.nlm.nih.gov/pubmed/28181483 http://dx.doi.org/10.1038/srep42006

Ejemplares similares

Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation
por: Kinsella, Sinéad, et al.
Publicado: (2018)

Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia123
por: Kinsella, Sinéad, et al.
Publicado: (2016)

TGF-β1 activates two distinct type I receptors in neurons: implications for neuronal NF-κB signaling
por: König, Hans-Georg, et al.
Publicado: (2005)

The negative feedback loop of NF-κB/miR-376b/NFKBIZ in septic acute kidney injury
por: Liu, Zhiwen, et al.
Publicado: (2020)

HBXIP activates the PPARδ/NF-κB feedback loop resulting in cell proliferation
por: Liu, Qian, et al.
Publicado: (2017)

Positive Feedback Promotes Oscillations in Negative Feedback Loops
por: Ananthasubramaniam, Bharath, et al.
Publicado: (2014)

COMMD7 is correlated with a novel NF-κB positive feedback loop in hepatocellular carcinoma
por: Zheng, Lu, et al.
Publicado: (2016)

Expanding the Substantial Interactome of NEMO Using Protein Microarrays
por: Fenner, Beau J., et al.
Publicado: (2010)

PATZ1 induces PP4R2 to form a negative feedback loop on IKK/NF-κB signaling in lung cancer
por: Ho, Ming-Yi, et al.
Publicado: (2016)

Determining zebrafish dorsal organizer size by a negative feedback loop between canonical/non-canonical Wnts and Tlr4/NFκB
por: Zou, Juqi, et al.
Publicado: (2023)

lncRNA‐NKILA/NF‐κB feedback loop modulates laryngeal cancer cell proliferation, invasion, and radioresistance
por: Yang, Tao, et al.
Publicado: (2018)

A novel positive feedback-loop between the HTLV-1 oncoprotein Tax and NF-κB activity in T-cells
por: Millen, Sebastian, et al.
Publicado: (2020)

Pin1 promotes pancreatic cancer progression and metastasis by activation of NF‐κB‐IL‐18 feedback loop
por: Sun, Qiqing, et al.
Publicado: (2020)

A negative feedback loop involving NF-κB/TIR8 regulates IL-1β-induced epithelial- myofibroblast transdifferentiation in human tubular cells
por: Jiang, Keguo, et al.
Publicado: (2021)

IκBɛ provides negative feedback to control NF-κB oscillations, signaling dynamics, and inflammatory gene expression
por: Kearns, Jeffrey D., et al.
Publicado: (2006)

Regulatory feedback loop between TP73 and TRIM32
por: Gonzalez-Cano, L, et al.
Publicado: (2013)

Gastric Hyperplasia and Increased Proliferative Responses of Lymphocytes in Mice Lacking the COOH-terminal Ankyrin Domain of NF-κB2
por: Ishikawa, Hideaki, et al.
Publicado: (1997)

STX2 promotes colorectal cancer metastasis through a positive feedback loop that activates the NF-κB pathway
por: Wang, Yongxia, et al.
Publicado: (2018)

A positive feedback loop between LINC01605 and NF-κB pathway promotes tumor growth in nasopharyngeal carcinoma
por: Zhao, Weiguo, et al.
Publicado: (2022)

An autoregulatory negative feedback loop controls thermomorphogenesis in Arabidopsis
por: Lee, Sanghwa, et al.
Publicado: (2021)

Designing negative feedback loops in enzymatic coacervate droplets
por: Modi, Nisha, et al.
Publicado: (2023)

Fas-associated factor (Faf1) is a novel CD40 interactor that regulates CD40-induced NF-κB activation via a negative feedback loop
por: Elmetwali, T, et al.
Publicado: (2014)

Telomerase reverse transcriptase acts in a feedback loop with NF-κB pathway to regulate macrophage polarization in alcoholic liver disease
por: Wu, Xiao-qin, et al.
Publicado: (2016)

Feedback loop in miR‐449b‐3p/ADAM17/NF‐κB promotes metastasis in nasopharyngeal carcinoma
por: Fei, Qian, et al.
Publicado: (2019)

SLC26A3/NHERF2-IκB/NFκB/p65 feedback loop suppresses tumorigenesis and metastasis in colorectal cancer
por: Lin, Chunlin, et al.
Publicado: (2023)

Noise in transcription negative feedback loops: simulation and experimental analysis
por: Dublanche, Yann, et al.
Publicado: (2006)

Transcription of the Geminin gene is regulated by a negative-feedback loop
por: Ohno, Yoshinori, et al.
Publicado: (2014)

Homogeneous Time Constants Promote Oscillations in Negative Feedback Loops
por: Blanchini, Franco, et al.
Publicado: (2018)

The Ankyrin Repeat Domain 49 (ANKRD49) Augments Autophagy of Serum-Starved GC-1 Cells through the NF-κB Pathway
por: Wang, Hai-long, et al.
Publicado: (2015)

MK2 controls the level of negative feedback in the NF-κB pathway and is essential for vascular permeability and airway inflammation
por: Gorska, Magdalena M., et al.
Publicado: (2007)

Inhibitory feedback control of NF-κB signalling in health and disease
por: Prescott, Jack A., et al.
Publicado: (2021)

USP15 inhibits multiple myeloma cell apoptosis through activating a feedback loop with the transcription factor NF-κBp65
por: Zhou, Lili, et al.
Publicado: (2018)

Arsenic trioxide reverses the chemoresistance in hepatocellular carcinoma: a targeted intervention of 14–3-3η/NF-κB feedback loop
por: Qiu, Yongxin, et al.
Publicado: (2018)

SNHG16/miR‐605‐3p/TRAF6/NF‐κB feedback loop regulates hepatocellular carcinoma metastasis
por: Hu, Yi‐Lin, et al.
Publicado: (2020)

Self-enforcing HMGB1/NF-κB/HIF-1α Feedback Loop Promotes Cisplatin Resistance in Hepatocellular Carcinoma Cells
por: Song, Yang, et al.
Publicado: (2020)

Melatonin alleviates intervertebral disc degeneration by disrupting the IL-1β/NF-κB-NLRP3 inflammasome positive feedback loop
por: Chen, Fan, et al.
Publicado: (2020)

Ankyrin‐2 genetic variants: A case of Ankyrin‐B syndrome
por: Song, Jin, et al.
Publicado: (2022)

A negative feedback loop attenuates EGF-induced morphological changes
Publicado: (1991)

Structure and function of negative feedback loops at the interface of genetic and metabolic networks
por: Krishna, Sandeep, et al.
Publicado: (2006)

Control of arbuscule development by a transcriptional negative feedback loop in Medicago
por: Zhang, Qiang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_r814v10vr3b1p521nk7qunig9n