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Meta‐analysis of individual‐patient data from EVAR‐1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years

BACKGROUND: The erosion of the early mortality advantage of elective endovascular aneurysm repair (EVAR) compared with open repair of abdominal aortic aneurysm remains without a satisfactory explanation. METHODS: An individual‐patient data meta‐analysis of four multicentre randomized trials of EVAR...

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Detalles Bibliográficos
Autores principales:	Powell, J. T., Sweeting, M. J., Ulug, P., Blankensteijn, J. D., Lederle, F. A., Becquemin, J.‐P., Greenhalgh, R. M., Beard, J. D., Buxton, M. J., Brown, L. C., Harris, P. L., Rose, J. D. G., Russell, I. T., Sculpher, M. J., Thompson, S. G., Lilford, R.J., Bell, P. R. F., Whitaker, S.C., Poole‐Wilson, the late P.A., Ruckley, C. V., Campbell, W. B., Dean, M. R. E., Ruttley, M. S. T., Coles, E. C., Halliday, A., Gibbs, S. J., Epstein, D., Hannon, R. J., Johnston, L., Bradbury, A. W., Henderson, M. J., Parvin, S. D., Shepherd, D. F. C., Mitchell, A. W., Edwards, P. R., Abbott, G. T., Higman, D. J., Vohra, A., Ashley, S., Robottom, C., Wyatt, M. G., Byrne, D., Edwards, R., Leiberman, D. P., McCarter, D. H., Taylor, P. R., Reidy, J. F., Wilkinson, A. R., Ettles, D. F., Clason, A. E., Leen, G. L. S., Wilson, N. V., Downes, M., Walker, S. R., Lavelle, J. M., Gough, M. J., McPherson, S., Scott, D. J. A., Kessell, D. O., Naylor, R., Sayers, R., Fishwick, N. G., Gould, D. A., Walker, M. G., Chalmers, N. C., Garnham, A., Collins, M. A., Gaines, P. A., Ashour, M. Y., Uberoi, R., Braithwaite, B., Whitaker, S. C., Davies, J. N., Travis, S., Hamilton, G., Platts, A., Shandall, A., Sullivan, B. A., Sobeh, M., Matson, M., Fox, A. D., Orme, R., Yusef, W., Doyle, T., Horrocks, M., Hardman, J., Blair, P. H. B., Ellis, P. K., Morris, G., Odurny, A., Vohra, R., Duddy, M., Thompson, M., Loosemore, T. M. L., Belli, A. M., Morgan, R., Adiseshiah, M., Brookes, J. A. S., McCollum, C. N., Ashleigh, R., Aukett, M., Baker, S., Barbe, E., Batson, N., Bell, J., Blundell, J., Boardley, D., Boyes, S., Brown, O., Bryce, J., Carmichael, M., Chance, T., Coleman, J., Cosgrove, C., Curran, G., Dennison, T., Devine, C., Dewhirst, N., Errington, B., Farrell, H., Fisher, C., Fulford, P., Gough, M., Graham, C., Hooper, R., Horne, G., Horrocks, L., Hughes, B., Hutchings, T., Ireland, M., Judge, C., Kelly, L., Kemp, J., Kite, A., Kivela, M., Lapworth, M., Lee, C., Linekar, L., Mahmood, A., March, L., Martin, J., Matharu, N., McGuigen, K., Morris‐Vincent, P., Murray, S., Murtagh, A., Owen, G., Ramoutar, V., Rippin, C., Rowley, J., Sinclair, J., Spencer, S., Taylor, V., Tomlinson, C., Ward, S., Wealleans, V., West, J., White, K., Williams, J., Wilson, L., Grobbee, D. E., Bak, A. A. A., Buth, J., Pattynama, P. M., Verhoeven, E. L. G., van Voorthuisen, A. E., Balm, R., Cuypers, P. W. M., Prinssen, M., van Sambeek, M. R. H. M., Baas, A. F., Hunink, M. G., van Engelshoven, J. M., Jacobs, M. J. H. M., de Mol, B. A. J. M., van Bockel, J. H., Reekers, J., Tielbeek, X., Wisselink, W., Boekema, N., Heuveling, L. M., Sikking, I., de Bruin, J. L., Tielbeek, A.V., Reekers, J. A., Pattynama, P., Prins, T., van der Ham, A. C., van der Velden, J. J. I. M., van Sterkenburg, S. M. M., ten Haken, G. B., Bruijninckx, C. M. A., van Overhagen, H., Tutein Nolthenius, R. P., Hendriksz, T. R., Teijink, J. A. W., Odink, H. F., de Smet, A. A. E. A., Vroegindeweij, D., van Loenhout, R. M. M., Rutten, M. J., Hamming, J. F., Lampmann, L. E. H., Bender, M. H. M., Pasmans, H., Vahl, A. C., de Vries, C., Mackaay, A. J. C., van Dortmont, L. M. C., van der Vliet, A. J., Schultze Kool, L. J., Boomsma, J. H. B., van Dop, H. R., de Mol van Otterloo, J. C. A., de Rooij, T. P. W., Smits, T. M., Yilmaz, E. N., van den Berg, F. G., Visser, M. J. T., van der Linden, E., Schurink, G. W. H., de Haan, M., Smeets, H. J., Stabel, P., van Elst, F., Poniewierski, J., Vermassen, F. E. G., Freischlag, J. A., Kohler, T. R., Latts, E., Matsumura, J., Padberg, F. T., Kyriakides, T. C., Swanson, K. M., Guarino, P., Peduzzi, P., Antonelli, M., Cushing, C., Davis, E., Durant, L., Joyner, S., Kossack, the late A., LeGwin, Mary, McBride, V., O'Connor, T., Poulton, J., Stratton, the late S., Zellner, S., Snodgrass, A. J., Thornton, J., Haakenson, C. M., Stroupe, K.T., Jonk, Y., Hallett, J. W., Hertzer, N., Towne, J., Katz, D. A., Karrison, T., Matts, J. P., Marottoli, R., Kasl, S., Mehta, R., Feldman, R., Farrell, W., Allore, H., Perry, E., Niederman, J., Randall, F., Zeman, M., Beckwith, the late D., O'Leary, T. J., Huang, G. D., Bader, M., Ketteler, E. R., Kingsley, D. D., Marek, J. M., Massen, R. J., Matteson, B. D., Pitcher, J. D., Langsfeld, M., Corson, J. D., Goff, J. M., Kasirajan, K., Paap, C., Robertson, D. C., Salam, A., Veeraswamy, R., Milner, R., Guidot, J., Lal, B. K., Busuttil, S. J., Lilly, M. P., Braganza, M., Ellis, K., Patterson, M. A., Jordan, W. D., Whitley, D., Taylor, S., Passman, M., Kerns, D., Inman, C., Poirier, J., Ebaugh, J., Raffetto, J., Chew, D., Lathi, S., Owens, C., Hickson, K., Dosluoglu, H. H., Eschberger, K., Kibbe, M. R., Baraniewski, H. M., Endo, M., Busman, A., Meadows, W., Evans, M., Giglia, J. S., El Sayed, H., Reed, A. B., Ruf, M., Ross, S., Jean‐Claude, J. M., Pinault, G., Kang, P., White, N., Eiseman, M., Jones, the late R., Timaran, C. H., Modrall, J. G., Welborn, M. B., Lopez, J., Nguyen, T., Chacko, J. K. Y., Granke, K., Vouyouka, A. G., Olgren, E., Chand, P., Allende, B., Ranella, M., Yales, C., Whitehill, T. A., Krupski, the late W. C., Nehler, M. R., Johnson, S. P., Jones, D. N., Strecker, P., Bhola, M. A., Shortell, C. K., Gray, J. L., Lawson, J. H., McCann, R., Sebastian, M.W., Kistler Tetterton, J., Blackwell, C., Prinzo, P. A., Lee, N., Cerveira, J. J., Zickler, R. W., Hauck, K. A., Berceli, S. A., Lee, W. A., Ozaki, C. K., Nelson, P. R., Irwin, A. S., Baum, R., Aulivola, B., Rodriguez, H., Littooy, F. N., Greisler, H., O'Sullivan, M. T., Kougias, P., Lin, P. H., Bush, R. L., Guinn, G., Bechara, C., Cagiannos, C., Pisimisis, G., Barshes, N., Pillack, S., Guillory, B., Cikrit, D., Lalka, S. G., Lemmon, G., Nachreiner, R., Rusomaroff, M., O'Brien, E., Cullen, J. J., Hoballah, J., Sharp, W. J., McCandless, J. L., Beach, V., Minion, D., Schwarcz, T. H., Kimbrough, J., Ashe, L., Rockich, A., Warner‐Carpenter, J., Moursi, M., Eidt, J. F., Brock, S., Bianchi, C., Bishop, V., Gordon, I. L., Fujitani, R., Kubaska, S. M., Behdad, M., Azadegan, R., Ma Agas, C., Zalecki, K., Hoch, J. R., Carr, S. C., Acher, C., Schwarze, M., Tefera, G., Mell, M., Dunlap, B., Rieder, J., Stuart, J. M., Weiman, D. S., Abul‐Khoudoud, O., Garrett, H. E., Walsh, S. M., Wilson, K. L., Seabrook, G. R., Cambria, R. A., Brown, K. R., Lewis, B. D., Framberg, S., Kallio, C., Barke, R. A., Santilli, S. M., d'Audiffret, A. C., Oberle, N., Proebstle, C., Johnson, L. L., Jacobowitz, G. R., Cayne, N., Rockman, C., Adelman, M., Gagne, P., Nalbandian, M., Caropolo, L. J., Pipinos, I. I., Johanning, J., Lynch, T., DeSpiegelaere, H., Purviance, G., Zhou, W., Dalman, R., Lee, J. T., Safadi, B., Coogan, S. M., Wren, S. M., Bahmani, D. D., Maples, D., Thunen, S., Golden, M. A., Mitchell, M. E., Fairman, R., Reinhardt, S., Wilson, M. A., Tzeng, E., Muluk, S., Peterson, N. M., Foster, M., Edwards, J., Moneta, G. L., Landry, G., Taylor, L., Yeager, R., Cannady, E., Treiman, G., Hatton‐Ward, S., Salabsky, the late B., Kansal, N., Owens, E., Estes, M., Forbes, B. A., Sobotta, C., Rapp, J. H., Reilly, L. M., Perez, S. L., Yan, K., Sarkar, R., Dwyer, S. S., Perez, S., Chong, K., Hatsukami, T. S., Glickerman, D. G., Sobel, M., Burdick, T. S., Pedersen, K., Cleary, P., Back, M., Bandyk, D., Johnson, B., Shames, M., Reinhard, R. L., Thomas, S. C., Hunter, G. C., Leon, L. R., Westerband, A., Guerra, R. J., Riveros, M., Mills, J. L., Hughes, J. D., Escalante, A. M., Psalms, S. B., Day, N. N., Macsata, R., Sidawy, A., Weiswasser, J., Arora, S., Jasper, B. J., Dardik, A., Gahtan, V., Muhs, B. E., Sumpio, B. E., Gusberg, R. J., Spector, M., Pollak, J., Aruny, J., Kelly, E. L., Wong, J., Vasilas, P., Joncas, C., Gelabert, H. A., DeVirgillio, C., Rigberg, D. A., Cole, L., Marzelle, J., Sapoval, M., Favre, J.‐P., Watelet, J., Lermusiaux, P., Lepage, E., Hemery, F., Dolbeau, G., Hawajry, N., Cunin, P., Harris, P., Stockx, L., Chatellier, G., Mialhe, C., Fiessinger, J.‐N., Pagny, L., Kobeiter, H., Boissier, C., Lacroix, P., Ledru, F., Pinot, J.‐J., Deux, J.‐F., Tzvetkov, B., Duvaldestin, P., Jourdain, C., David, V., Enouf, D., Ady, N., Krimi, A., Boudjema, N., Jousset, Y., Enon, B., Blin, V., Picquet, J., L'Hoste, P., Thouveny, F., Borie, H., Kowarski, S., Pernes, J.‐M., Auguste, M., Desgranges, P., Allaire, E., Meaulle, P.‐Y., Chaix, D., Juliae, P., Fabiani, J. N., Chevalier, P., Combes, M., Seguin, A., Belhomme, D., Baque, J., Pellerin, O., Favre, J. P., Barral, X., Veyret, C., Peillon, C., Plissonier, D., Thomas, P., Clavier, E., Martinez, R., Bleuet, F., C, Dupreix, Verhoye, J. P., Langanay, T., Heautot, J. F., Koussa, M., Haulon, S., Halna, P., Destrieux, L., Lions, C., Wiloteaux, S., Beregi, J. P., Bergeron, P., Patra, P., Costargent, A., Chaillou, P., D'Alicourt, A., Goueffic, Y., Cheysson, E., Parrot, A., Garance, P., Demon, A., Tyazi, A., Pillet, J.‐C., Lescalie, F., Tilly, G., Steinmetz, E., Favier, C., Brenot, R., Krause, D., Cercueil, J. P., Vahdat, O., Sauer, M., Soula, P., Querian, A., Garcia, O., Levade, M., Colombier, D., Cardon, J.‐M., Joyeux, A., Borrelly, P., Dogas, G., Magnan, P.‐É., Branchereau, A., Bartoli, J.‐M., Hassen‐Khodja, R., Batt, M., Planchard, P.‐F., Bouillanne, P.‐J., Haudebourg, P., Bayne, J., Gouny, P., Badra, A., Braesco, J., Nonent, M., Lucas, A., Cardon, A., Kerdiles, Y., Rolland, Y., Kassab, M., Brillu, C., Goubault, F., Tailboux, L., Darrieux, H., Briand, O., Maillard, J.‐C., Varty, K., Cousins, C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2017
Materias:	Systematic Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299468/ https://www.ncbi.nlm.nih.gov/pubmed/28160528 http://dx.doi.org/10.1002/bjs.10430

_version_	1782506031455141888
author	Powell, J. T. Sweeting, M. J. Ulug, P. Blankensteijn, J. D. Lederle, F. A. Becquemin, J.‐P. Greenhalgh, R. M. Greenhalgh, R. M. Beard, J. D. Buxton, M. J. Brown, L. C. Harris, P. L. Powell, J. T. Rose, J. D. G. Russell, I. T. Sculpher, M. J. Thompson, S. G. Lilford, R.J. Bell, P. R. F. Greenhalgh, R. M. Whitaker, S.C. Poole‐Wilson, the late P.A. Ruckley, C. V. Campbell, W. B. Dean, M. R. E. Ruttley, M. S. T. Coles, E. C. Powell, J. T. Halliday, A. Gibbs, S. J. Brown, L. C. Epstein, D. Sculpher, M. J. Thompson, S. G. Hannon, R. J. Johnston, L. Bradbury, A. W. Henderson, M. J. Parvin, S. D. Shepherd, D. F. C. Greenhalgh, R. M. Mitchell, A. W. Edwards, P. R. Abbott, G. T. Higman, D. J. Vohra, A. Ashley, S. Robottom, C. Wyatt, M. G. Rose, J. D. G. Byrne, D. Edwards, R. Leiberman, D. P. McCarter, D. H. Taylor, P. R. Reidy, J. F. Wilkinson, A. R. Ettles, D. F. Clason, A. E. Leen, G. L. S. Wilson, N. V. Downes, M. Walker, S. R. Lavelle, J. M. Gough, M. J. McPherson, S. Scott, D. J. A. Kessell, D. O. Naylor, R. Sayers, R. Fishwick, N. G. Harris, P. L. Gould, D. A. Walker, M. G. Chalmers, N. C. Garnham, A. Collins, M. A. Beard, J. D. Gaines, P. A. Ashour, M. Y. Uberoi, R. Braithwaite, B. Whitaker, S. C. Davies, J. N. Travis, S. Hamilton, G. Platts, A. Shandall, A. Sullivan, B. A. Sobeh, M. Matson, M. Fox, A. D. Orme, R. Yusef, W. Doyle, T. Horrocks, M. Hardman, J. Blair, P. H. B. Ellis, P. K. Morris, G. Odurny, A. Vohra, R. Duddy, M. Thompson, M. Loosemore, T. M. L. Belli, A. M. Morgan, R. Adiseshiah, M. Brookes, J. A. S. McCollum, C. N. Ashleigh, R. Aukett, M. Baker, S. Barbe, E. Batson, N. Bell, J. Blundell, J. Boardley, D. Boyes, S. Brown, O. Bryce, J. Carmichael, M. Chance, T. Coleman, J. Cosgrove, C. Curran, G. Dennison, T. Devine, C. Dewhirst, N. Errington, B. Farrell, H. Fisher, C. Fulford, P. Gough, M. Graham, C. Hooper, R. Horne, G. Horrocks, L. Hughes, B. Hutchings, T. Ireland, M. Judge, C. Kelly, L. Kemp, J. Kite, A. Kivela, M. Lapworth, M. Lee, C. Linekar, L. Mahmood, A. March, L. Martin, J. Matharu, N. McGuigen, K. Morris‐Vincent, P. Murray, S. Murtagh, A. Owen, G. Ramoutar, V. Rippin, C. Rowley, J. Sinclair, J. Spencer, S. Taylor, V. Tomlinson, C. Ward, S. Wealleans, V. West, J. White, K. Williams, J. Wilson, L. Grobbee, D. E. Blankensteijn, J. D. Bak, A. A. A. Buth, J. Pattynama, P. M. Verhoeven, E. L. G. van Voorthuisen, A. E. Blankensteijn, J. D. Balm, R. Buth, J. Cuypers, P. W. M. Grobbee, D. E. Prinssen, M. van Sambeek, M. R. H. M. Verhoeven, E. L. G. Baas, A. F. Hunink, M. G. van Engelshoven, J. M. Jacobs, M. J. H. M. de Mol, B. A. J. M. van Bockel, J. H. Balm, R. Reekers, J. Tielbeek, X. Verhoeven, E. L. G. Wisselink, W. Boekema, N. Heuveling, L. M. Sikking, I. Prinssen, M. Balm, R. Blankensteijn, J. D. Buth, J. Cuypers, P. W. M. van Sambeek, M. R. H. M. Verhoeven, E. L. G. de Bruin, J. L. Baas, A. F. Blankensteijn, J. D. Prinssen, M. Buth, J. Tielbeek, A.V. Blankensteijn, J. D. Balm, R. Reekers, J. A. van Sambeek, M. R. H. M. Pattynama, P. Verhoeven, E. L. G. Prins, T. van der Ham, A. C. van der Velden, J. J. I. M. van Sterkenburg, S. M. M. ten Haken, G. B. Bruijninckx, C. M. A. van Overhagen, H. Tutein Nolthenius, R. P. Hendriksz, T. R. Teijink, J. A. W. Odink, H. F. de Smet, A. A. E. A. Vroegindeweij, D. van Loenhout, R. M. M. Rutten, M. J. Hamming, J. F. Lampmann, L. E. H. Bender, M. H. M. Pasmans, H. Vahl, A. C. de Vries, C. Mackaay, A. J. C. van Dortmont, L. M. C. van der Vliet, A. J. Schultze Kool, L. J. Boomsma, J. H. B. van Dop, H. R. de Mol van Otterloo, J. C. A. de Rooij, T. P. W. Smits, T. M. Yilmaz, E. N. Wisselink, W. van den Berg, F. G. Visser, M. J. T. van der Linden, E. Schurink, G. W. H. de Haan, M. Smeets, H. J. Stabel, P. van Elst, F. Poniewierski, J. Vermassen, F. E. G. Lederle, F. A. Freischlag, J. A. Kohler, T. R. Latts, E. Matsumura, J. Padberg, F. T. Kyriakides, T. C. Swanson, K. M. Guarino, P. Peduzzi, P. Antonelli, M. Cushing, C. Davis, E. Durant, L. Joyner, S. Kossack, the late A. Kyriakides, T. C. LeGwin, Mary McBride, V. O'Connor, T. Poulton, J. Stratton, the late S. Zellner, S. Snodgrass, A. J. Thornton, J. Swanson, K. M. Haakenson, C. M. Stroupe, K.T. Jonk, Y. Hallett, J. W. Hertzer, N. Towne, J. Katz, D. A. Karrison, T. Matts, J. P. Marottoli, R. Kasl, S. Mehta, R. Feldman, R. Farrell, W. Allore, H. Perry, E. Niederman, J. Randall, F. Zeman, M. Beckwith, the late D. O'Leary, T. J. Huang, G. D. Latts, E. Bader, M. Ketteler, E. R. Kingsley, D. D. Marek, J. M. Massen, R. J. Matteson, B. D. Pitcher, J. D. Langsfeld, M. Corson, J. D. Goff, J. M. Kasirajan, K. Paap, C. Robertson, D. C. Salam, A. Veeraswamy, R. Milner, R. Kasirajan, K. Guidot, J. Lal, B. K. Busuttil, S. J. Lilly, M. P. Braganza, M. Ellis, K. Patterson, M. A. Jordan, W. D. Whitley, D. Taylor, S. Passman, M. Kerns, D. Inman, C. Poirier, J. Ebaugh, J. Raffetto, J. Chew, D. Lathi, S. Owens, C. Hickson, K. Dosluoglu, H. H. Eschberger, K. Kibbe, M. R. Baraniewski, H. M. Matsumura, J. Endo, M. Busman, A. Meadows, W. Evans, M. Giglia, J. S. El Sayed, H. Reed, A. B. Ruf, M. Ross, S. Jean‐Claude, J. M. Pinault, G. Kang, P. White, N. Eiseman, M. Jones, the late R. Timaran, C. H. Modrall, J. G. Welborn, M. B. Lopez, J. Nguyen, T. Chacko, J. K. Y. Granke, K. Vouyouka, A. G. Olgren, E. Chand, P. Allende, B. Ranella, M. Yales, C. Whitehill, T. A. Krupski, the late W. C. Nehler, M. R. Johnson, S. P. Jones, D. N. Strecker, P. Bhola, M. A. Shortell, C. K. Gray, J. L. Lawson, J. H. McCann, R. Sebastian, M.W. Kistler Tetterton, J. Blackwell, C. Prinzo, P. A. Lee, N. Padberg, F. T. Cerveira, J. J. Lal, B. K. Zickler, R. W. Hauck, K. A. Berceli, S. A. Lee, W. A. Ozaki, C. K. Nelson, P. R. Irwin, A. S. Baum, R. Aulivola, B. Rodriguez, H. Littooy, F. N. Greisler, H. O'Sullivan, M. T. Kougias, P. Lin, P. H. Bush, R. L. Guinn, G. Bechara, C. Cagiannos, C. Pisimisis, G. Barshes, N. Pillack, S. Guillory, B. Cikrit, D. Lalka, S. G. Lemmon, G. Nachreiner, R. Rusomaroff, M. O'Brien, E. Cullen, J. J. Hoballah, J. Sharp, W. J. McCandless, J. L. Beach, V. Minion, D. Schwarcz, T. H. Kimbrough, J. Ashe, L. Rockich, A. Warner‐Carpenter, J. Moursi, M. Eidt, J. F. Brock, S. Bianchi, C. Bishop, V. Gordon, I. L. Fujitani, R. Kubaska, S. M. Behdad, M. Azadegan, R. Ma Agas, C. Zalecki, K. Hoch, J. R. Carr, S. C. Acher, C. Schwarze, M. Tefera, G. Mell, M. Dunlap, B. Rieder, J. Stuart, J. M. Weiman, D. S. Abul‐Khoudoud, O. Garrett, H. E. Walsh, S. M. Wilson, K. L. Seabrook, G. R. Cambria, R. A. Brown, K. R. Lewis, B. D. Framberg, S. Kallio, C. Barke, R. A. Santilli, S. M. d'Audiffret, A. C. Oberle, N. Proebstle, C. Johnson, L. L. Jacobowitz, G. R. Cayne, N. Rockman, C. Adelman, M. Gagne, P. Nalbandian, M. Caropolo, L. J. Pipinos, I. I. Johanning, J. Lynch, T. DeSpiegelaere, H. Purviance, G. Zhou, W. Dalman, R. Lee, J. T. Safadi, B. Coogan, S. M. Wren, S. M. Bahmani, D. D. Maples, D. Thunen, S. Golden, M. A. Mitchell, M. E. Fairman, R. Reinhardt, S. Wilson, M. A. Tzeng, E. Muluk, S. Peterson, N. M. Foster, M. Edwards, J. Moneta, G. L. Landry, G. Taylor, L. Yeager, R. Cannady, E. Treiman, G. Hatton‐Ward, S. Salabsky, the late B. Kansal, N. Owens, E. Estes, M. Forbes, B. A. Sobotta, C. Rapp, J. H. Reilly, L. M. Perez, S. L. Yan, K. Sarkar, R. Dwyer, S. S. Perez, S. Chong, K. Kohler, T. R. Hatsukami, T. S. Glickerman, D. G. Sobel, M. Burdick, T. S. Pedersen, K. Cleary, P. Back, M. Bandyk, D. Johnson, B. Shames, M. Reinhard, R. L. Thomas, S. C. Hunter, G. C. Leon, L. R. Westerband, A. Guerra, R. J. Riveros, M. Mills, J. L. Hughes, J. D. Escalante, A. M. Psalms, S. B. Day, N. N. Macsata, R. Sidawy, A. Weiswasser, J. Arora, S. Jasper, B. J. Dardik, A. Gahtan, V. Muhs, B. E. Sumpio, B. E. Gusberg, R. J. Spector, M. Pollak, J. Aruny, J. Kelly, E. L. Wong, J. Vasilas, P. Joncas, C. Gelabert, H. A. DeVirgillio, C. Rigberg, D. A. Cole, L. Becquemin, J.‐P. Marzelle, J. Becquemin, J.‐P. Sapoval, M. Becquemin, J.‐P. Favre, J.‐P. Watelet, J. Lermusiaux, P. Sapoval, M. Lepage, E. Hemery, F. Dolbeau, G. Hawajry, N. Cunin, P. Harris, P. Stockx, L. Chatellier, G. Mialhe, C. Fiessinger, J.‐N. Pagny, L. Kobeiter, H. Boissier, C. Lacroix, P. Ledru, F. Pinot, J.‐J. Deux, J.‐F. Tzvetkov, B. Duvaldestin, P. Watelet, J. Jourdain, C. David, V. Enouf, D. Ady, N. Krimi, A. Boudjema, N. Jousset, Y. Enon, B. Blin, V. Picquet, J. L'Hoste, P. Thouveny, F. Borie, H. Kowarski, S. Pernes, J.‐M. Auguste, M. Becquemin, J.‐P. Desgranges, P. Allaire, E. Marzelle, J. Kobeiter, H. Meaulle, P.‐Y. Chaix, D. Juliae, P. Fabiani, J. N. Chevalier, P. Combes, M. Seguin, A. Belhomme, D. Sapoval, M. Baque, J. Pellerin, O. Favre, J. P. Barral, X. Veyret, C. Watelet, J. Peillon, C. Plissonier, D. Thomas, P. Clavier, E. Lermusiaux, P. Martinez, R. Bleuet, F. C, Dupreix Verhoye, J. P. Langanay, T. Heautot, J. F. Koussa, M. Haulon, S. Halna, P. Destrieux, L. Lions, C. Wiloteaux, S. Beregi, J. P. Bergeron, P. Pinot, J.‐J. Patra, P. Costargent, A. Chaillou, P. D'Alicourt, A. Goueffic, Y. Cheysson, E. Parrot, A. Garance, P. Demon, A. Tyazi, A. Pillet, J.‐C. Lescalie, F. Tilly, G. Steinmetz, E. Favier, C. Brenot, R. Krause, D. Cercueil, J. P. Vahdat, O. Sauer, M. Soula, P. Querian, A. Garcia, O. Levade, M. Colombier, D. Cardon, J.‐M. Joyeux, A. Borrelly, P. Dogas, G. Magnan, P.‐É. Branchereau, A. Bartoli, J.‐M. Hassen‐Khodja, R. Batt, M. Planchard, P.‐F. Bouillanne, P.‐J. Haudebourg, P. Bayne, J. Gouny, P. Badra, A. Braesco, J. Nonent, M. Lucas, A. Cardon, A. Kerdiles, Y. Rolland, Y. Kassab, M. Brillu, C. Goubault, F. Tailboux, L. Darrieux, H. Briand, O. Maillard, J.‐C. Varty, K. Cousins, C.
author_facet	Powell, J. T. Sweeting, M. J. Ulug, P. Blankensteijn, J. D. Lederle, F. A. Becquemin, J.‐P. Greenhalgh, R. M. Greenhalgh, R. M. Beard, J. D. Buxton, M. J. Brown, L. C. Harris, P. L. Powell, J. T. Rose, J. D. G. Russell, I. T. Sculpher, M. J. Thompson, S. G. Lilford, R.J. Bell, P. R. F. Greenhalgh, R. M. Whitaker, S.C. Poole‐Wilson, the late P.A. Ruckley, C. V. Campbell, W. B. Dean, M. R. E. Ruttley, M. S. T. Coles, E. C. Powell, J. T. Halliday, A. Gibbs, S. J. Brown, L. C. Epstein, D. Sculpher, M. J. Thompson, S. G. Hannon, R. J. Johnston, L. Bradbury, A. W. Henderson, M. J. Parvin, S. D. Shepherd, D. F. C. Greenhalgh, R. M. Mitchell, A. W. Edwards, P. R. Abbott, G. T. Higman, D. J. Vohra, A. Ashley, S. Robottom, C. Wyatt, M. G. Rose, J. D. G. Byrne, D. Edwards, R. Leiberman, D. P. McCarter, D. H. Taylor, P. R. Reidy, J. F. Wilkinson, A. R. Ettles, D. F. Clason, A. E. Leen, G. L. S. Wilson, N. V. Downes, M. Walker, S. R. Lavelle, J. M. Gough, M. J. McPherson, S. Scott, D. J. A. Kessell, D. O. Naylor, R. Sayers, R. Fishwick, N. G. Harris, P. L. Gould, D. A. Walker, M. G. Chalmers, N. C. Garnham, A. Collins, M. A. Beard, J. D. Gaines, P. A. Ashour, M. Y. Uberoi, R. Braithwaite, B. Whitaker, S. C. Davies, J. N. Travis, S. Hamilton, G. Platts, A. Shandall, A. Sullivan, B. A. Sobeh, M. Matson, M. Fox, A. D. Orme, R. Yusef, W. Doyle, T. Horrocks, M. Hardman, J. Blair, P. H. B. Ellis, P. K. Morris, G. Odurny, A. Vohra, R. Duddy, M. Thompson, M. Loosemore, T. M. L. Belli, A. M. Morgan, R. Adiseshiah, M. Brookes, J. A. S. McCollum, C. N. Ashleigh, R. Aukett, M. Baker, S. Barbe, E. Batson, N. Bell, J. Blundell, J. Boardley, D. Boyes, S. Brown, O. Bryce, J. Carmichael, M. Chance, T. Coleman, J. Cosgrove, C. Curran, G. Dennison, T. Devine, C. Dewhirst, N. Errington, B. Farrell, H. Fisher, C. Fulford, P. Gough, M. Graham, C. Hooper, R. Horne, G. Horrocks, L. Hughes, B. Hutchings, T. Ireland, M. Judge, C. Kelly, L. Kemp, J. Kite, A. Kivela, M. Lapworth, M. Lee, C. Linekar, L. Mahmood, A. March, L. Martin, J. Matharu, N. McGuigen, K. Morris‐Vincent, P. Murray, S. Murtagh, A. Owen, G. Ramoutar, V. Rippin, C. Rowley, J. Sinclair, J. Spencer, S. Taylor, V. Tomlinson, C. Ward, S. Wealleans, V. West, J. White, K. Williams, J. Wilson, L. Grobbee, D. E. Blankensteijn, J. D. Bak, A. A. A. Buth, J. Pattynama, P. M. Verhoeven, E. L. G. van Voorthuisen, A. E. Blankensteijn, J. D. Balm, R. Buth, J. Cuypers, P. W. M. Grobbee, D. E. Prinssen, M. van Sambeek, M. R. H. M. Verhoeven, E. L. G. Baas, A. F. Hunink, M. G. van Engelshoven, J. M. Jacobs, M. J. H. M. de Mol, B. A. J. M. van Bockel, J. H. Balm, R. Reekers, J. Tielbeek, X. Verhoeven, E. L. G. Wisselink, W. Boekema, N. Heuveling, L. M. Sikking, I. Prinssen, M. Balm, R. Blankensteijn, J. D. Buth, J. Cuypers, P. W. M. van Sambeek, M. R. H. M. Verhoeven, E. L. G. de Bruin, J. L. Baas, A. F. Blankensteijn, J. D. Prinssen, M. Buth, J. Tielbeek, A.V. Blankensteijn, J. D. Balm, R. Reekers, J. A. van Sambeek, M. R. H. M. Pattynama, P. Verhoeven, E. L. G. Prins, T. van der Ham, A. C. van der Velden, J. J. I. M. van Sterkenburg, S. M. M. ten Haken, G. B. Bruijninckx, C. M. A. van Overhagen, H. Tutein Nolthenius, R. P. Hendriksz, T. R. Teijink, J. A. W. Odink, H. F. de Smet, A. A. E. A. Vroegindeweij, D. van Loenhout, R. M. M. Rutten, M. J. Hamming, J. F. Lampmann, L. E. H. Bender, M. H. M. Pasmans, H. Vahl, A. C. de Vries, C. Mackaay, A. J. C. van Dortmont, L. M. C. van der Vliet, A. J. Schultze Kool, L. J. Boomsma, J. H. B. van Dop, H. R. de Mol van Otterloo, J. C. A. de Rooij, T. P. W. Smits, T. M. Yilmaz, E. N. Wisselink, W. van den Berg, F. G. Visser, M. J. T. van der Linden, E. Schurink, G. W. H. de Haan, M. Smeets, H. J. Stabel, P. van Elst, F. Poniewierski, J. Vermassen, F. E. G. Lederle, F. A. Freischlag, J. A. Kohler, T. R. Latts, E. Matsumura, J. Padberg, F. T. Kyriakides, T. C. Swanson, K. M. Guarino, P. Peduzzi, P. Antonelli, M. Cushing, C. Davis, E. Durant, L. Joyner, S. Kossack, the late A. Kyriakides, T. C. LeGwin, Mary McBride, V. O'Connor, T. Poulton, J. Stratton, the late S. Zellner, S. Snodgrass, A. J. Thornton, J. Swanson, K. M. Haakenson, C. M. Stroupe, K.T. Jonk, Y. Hallett, J. W. Hertzer, N. Towne, J. Katz, D. A. Karrison, T. Matts, J. P. Marottoli, R. Kasl, S. Mehta, R. Feldman, R. Farrell, W. Allore, H. Perry, E. Niederman, J. Randall, F. Zeman, M. Beckwith, the late D. O'Leary, T. J. Huang, G. D. Latts, E. Bader, M. Ketteler, E. R. Kingsley, D. D. Marek, J. M. Massen, R. J. Matteson, B. D. Pitcher, J. D. Langsfeld, M. Corson, J. D. Goff, J. M. Kasirajan, K. Paap, C. Robertson, D. C. Salam, A. Veeraswamy, R. Milner, R. Kasirajan, K. Guidot, J. Lal, B. K. Busuttil, S. J. Lilly, M. P. Braganza, M. Ellis, K. Patterson, M. A. Jordan, W. D. Whitley, D. Taylor, S. Passman, M. Kerns, D. Inman, C. Poirier, J. Ebaugh, J. Raffetto, J. Chew, D. Lathi, S. Owens, C. Hickson, K. Dosluoglu, H. H. Eschberger, K. Kibbe, M. R. Baraniewski, H. M. Matsumura, J. Endo, M. Busman, A. Meadows, W. Evans, M. Giglia, J. S. El Sayed, H. Reed, A. B. Ruf, M. Ross, S. Jean‐Claude, J. M. Pinault, G. Kang, P. White, N. Eiseman, M. Jones, the late R. Timaran, C. H. Modrall, J. G. Welborn, M. B. Lopez, J. Nguyen, T. Chacko, J. K. Y. Granke, K. Vouyouka, A. G. Olgren, E. Chand, P. Allende, B. Ranella, M. Yales, C. Whitehill, T. A. Krupski, the late W. C. Nehler, M. R. Johnson, S. P. Jones, D. N. Strecker, P. Bhola, M. A. Shortell, C. K. Gray, J. L. Lawson, J. H. McCann, R. Sebastian, M.W. Kistler Tetterton, J. Blackwell, C. Prinzo, P. A. Lee, N. Padberg, F. T. Cerveira, J. J. Lal, B. K. Zickler, R. W. Hauck, K. A. Berceli, S. A. Lee, W. A. Ozaki, C. K. Nelson, P. R. Irwin, A. S. Baum, R. Aulivola, B. Rodriguez, H. Littooy, F. N. Greisler, H. O'Sullivan, M. T. Kougias, P. Lin, P. H. Bush, R. L. Guinn, G. Bechara, C. Cagiannos, C. Pisimisis, G. Barshes, N. Pillack, S. Guillory, B. Cikrit, D. Lalka, S. G. Lemmon, G. Nachreiner, R. Rusomaroff, M. O'Brien, E. Cullen, J. J. Hoballah, J. Sharp, W. J. McCandless, J. L. Beach, V. Minion, D. Schwarcz, T. H. Kimbrough, J. Ashe, L. Rockich, A. Warner‐Carpenter, J. Moursi, M. Eidt, J. F. Brock, S. Bianchi, C. Bishop, V. Gordon, I. L. Fujitani, R. Kubaska, S. M. Behdad, M. Azadegan, R. Ma Agas, C. Zalecki, K. Hoch, J. R. Carr, S. C. Acher, C. Schwarze, M. Tefera, G. Mell, M. Dunlap, B. Rieder, J. Stuart, J. M. Weiman, D. S. Abul‐Khoudoud, O. Garrett, H. E. Walsh, S. M. Wilson, K. L. Seabrook, G. R. Cambria, R. A. Brown, K. R. Lewis, B. D. Framberg, S. Kallio, C. Barke, R. A. Santilli, S. M. d'Audiffret, A. C. Oberle, N. Proebstle, C. Johnson, L. L. Jacobowitz, G. R. Cayne, N. Rockman, C. Adelman, M. Gagne, P. Nalbandian, M. Caropolo, L. J. Pipinos, I. I. Johanning, J. Lynch, T. DeSpiegelaere, H. Purviance, G. Zhou, W. Dalman, R. Lee, J. T. Safadi, B. Coogan, S. M. Wren, S. M. Bahmani, D. D. Maples, D. Thunen, S. Golden, M. A. Mitchell, M. E. Fairman, R. Reinhardt, S. Wilson, M. A. Tzeng, E. Muluk, S. Peterson, N. M. Foster, M. Edwards, J. Moneta, G. L. Landry, G. Taylor, L. Yeager, R. Cannady, E. Treiman, G. Hatton‐Ward, S. Salabsky, the late B. Kansal, N. Owens, E. Estes, M. Forbes, B. A. Sobotta, C. Rapp, J. H. Reilly, L. M. Perez, S. L. Yan, K. Sarkar, R. Dwyer, S. S. Perez, S. Chong, K. Kohler, T. R. Hatsukami, T. S. Glickerman, D. G. Sobel, M. Burdick, T. S. Pedersen, K. Cleary, P. Back, M. Bandyk, D. Johnson, B. Shames, M. Reinhard, R. L. Thomas, S. C. Hunter, G. C. Leon, L. R. Westerband, A. Guerra, R. J. Riveros, M. Mills, J. L. Hughes, J. D. Escalante, A. M. Psalms, S. B. Day, N. N. Macsata, R. Sidawy, A. Weiswasser, J. Arora, S. Jasper, B. J. Dardik, A. Gahtan, V. Muhs, B. E. Sumpio, B. E. Gusberg, R. J. Spector, M. Pollak, J. Aruny, J. Kelly, E. L. Wong, J. Vasilas, P. Joncas, C. Gelabert, H. A. DeVirgillio, C. Rigberg, D. A. Cole, L. Becquemin, J.‐P. Marzelle, J. Becquemin, J.‐P. Sapoval, M. Becquemin, J.‐P. Favre, J.‐P. Watelet, J. Lermusiaux, P. Sapoval, M. Lepage, E. Hemery, F. Dolbeau, G. Hawajry, N. Cunin, P. Harris, P. Stockx, L. Chatellier, G. Mialhe, C. Fiessinger, J.‐N. Pagny, L. Kobeiter, H. Boissier, C. Lacroix, P. Ledru, F. Pinot, J.‐J. Deux, J.‐F. Tzvetkov, B. Duvaldestin, P. Watelet, J. Jourdain, C. David, V. Enouf, D. Ady, N. Krimi, A. Boudjema, N. Jousset, Y. Enon, B. Blin, V. Picquet, J. L'Hoste, P. Thouveny, F. Borie, H. Kowarski, S. Pernes, J.‐M. Auguste, M. Becquemin, J.‐P. Desgranges, P. Allaire, E. Marzelle, J. Kobeiter, H. Meaulle, P.‐Y. Chaix, D. Juliae, P. Fabiani, J. N. Chevalier, P. Combes, M. Seguin, A. Belhomme, D. Sapoval, M. Baque, J. Pellerin, O. Favre, J. P. Barral, X. Veyret, C. Watelet, J. Peillon, C. Plissonier, D. Thomas, P. Clavier, E. Lermusiaux, P. Martinez, R. Bleuet, F. C, Dupreix Verhoye, J. P. Langanay, T. Heautot, J. F. Koussa, M. Haulon, S. Halna, P. Destrieux, L. Lions, C. Wiloteaux, S. Beregi, J. P. Bergeron, P. Pinot, J.‐J. Patra, P. Costargent, A. Chaillou, P. D'Alicourt, A. Goueffic, Y. Cheysson, E. Parrot, A. Garance, P. Demon, A. Tyazi, A. Pillet, J.‐C. Lescalie, F. Tilly, G. Steinmetz, E. Favier, C. Brenot, R. Krause, D. Cercueil, J. P. Vahdat, O. Sauer, M. Soula, P. Querian, A. Garcia, O. Levade, M. Colombier, D. Cardon, J.‐M. Joyeux, A. Borrelly, P. Dogas, G. Magnan, P.‐É. Branchereau, A. Bartoli, J.‐M. Hassen‐Khodja, R. Batt, M. Planchard, P.‐F. Bouillanne, P.‐J. Haudebourg, P. Bayne, J. Gouny, P. Badra, A. Braesco, J. Nonent, M. Lucas, A. Cardon, A. Kerdiles, Y. Rolland, Y. Kassab, M. Brillu, C. Goubault, F. Tailboux, L. Darrieux, H. Briand, O. Maillard, J.‐C. Varty, K. Cousins, C.
author_sort	Powell, J. T.
collection	PubMed
description	BACKGROUND: The erosion of the early mortality advantage of elective endovascular aneurysm repair (EVAR) compared with open repair of abdominal aortic aneurysm remains without a satisfactory explanation. METHODS: An individual‐patient data meta‐analysis of four multicentre randomized trials of EVAR versus open repair was conducted to a prespecified analysis plan, reporting on mortality, aneurysm‐related mortality and reintervention. RESULTS: The analysis included 2783 patients, with 14 245 person‐years of follow‐up (median 5·5 years). Early (0–6 months after randomization) mortality was lower in the EVAR groups (46 of 1393 versus 73 of 1390 deaths; pooled hazard ratio 0·61, 95 per cent c.i. 0·42 to 0·89; P = 0·010), primarily because 30‐day operative mortality was lower in the EVAR groups (16 deaths versus 40 for open repair; pooled odds ratio 0·40, 95 per cent c.i. 0·22 to 0·74). Later (within 3 years) the survival curves converged, remaining converged to 8 years. Beyond 3 years, aneurysm‐related mortality was significantly higher in the EVAR groups (19 deaths versus 3 for open repair; pooled hazard ratio 5·16, 1·49 to 17·89; P = 0·010). Patients with moderate renal dysfunction or previous coronary artery disease had no early survival advantage under EVAR. Those with peripheral artery disease had lower mortality under open repair (39 deaths versus 62 for EVAR; P = 0·022) in the period from 6 months to 4 years after randomization. CONCLUSION: The early survival advantage in the EVAR group, and its subsequent erosion, were confirmed. Over 5 years, patients of marginal fitness had no early survival advantage from EVAR compared with open repair. Aneurysm‐related mortality and patients with low ankle : brachial pressure index contributed to the erosion of the early survival advantage for the EVAR group. Trial registration numbers: EVAR‐1, ISRCTN55703451; DREAM (Dutch Randomized Endovascular Aneurysm Management), NCT00421330; ACE (Anévrysme de l'aorte abdominale, Chirurgie versus Endoprothèse), NCT00224718; OVER (Open Versus Endovascular Repair Trial for Abdominal Aortic Aneurysms), NCT00094575.
format	Online Article Text
id	pubmed-5299468
institution	National Center for Biotechnology Information
language	English
publishDate	2017
publisher	John Wiley & Sons, Ltd
record_format	MEDLINE/PubMed
spelling	pubmed-52994682017-02-22 Meta‐analysis of individual‐patient data from EVAR‐1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years Powell, J. T. Sweeting, M. J. Ulug, P. Blankensteijn, J. D. Lederle, F. A. Becquemin, J.‐P. Greenhalgh, R. M. Greenhalgh, R. M. Beard, J. D. Buxton, M. J. Brown, L. C. Harris, P. L. Powell, J. T. Rose, J. D. G. Russell, I. T. Sculpher, M. J. Thompson, S. G. Lilford, R.J. Bell, P. R. F. Greenhalgh, R. M. Whitaker, S.C. Poole‐Wilson, the late P.A. Ruckley, C. V. Campbell, W. B. Dean, M. R. E. Ruttley, M. S. T. Coles, E. C. Powell, J. T. Halliday, A. Gibbs, S. J. Brown, L. C. Epstein, D. Sculpher, M. J. Thompson, S. G. Hannon, R. J. Johnston, L. Bradbury, A. W. Henderson, M. J. Parvin, S. D. Shepherd, D. F. C. Greenhalgh, R. M. Mitchell, A. W. Edwards, P. R. Abbott, G. T. Higman, D. J. Vohra, A. Ashley, S. Robottom, C. Wyatt, M. G. Rose, J. D. G. Byrne, D. Edwards, R. Leiberman, D. P. McCarter, D. H. Taylor, P. R. Reidy, J. F. Wilkinson, A. R. Ettles, D. F. Clason, A. E. Leen, G. L. S. Wilson, N. V. Downes, M. Walker, S. R. Lavelle, J. M. Gough, M. J. McPherson, S. Scott, D. J. A. Kessell, D. O. Naylor, R. Sayers, R. Fishwick, N. G. Harris, P. L. Gould, D. A. Walker, M. G. Chalmers, N. C. Garnham, A. Collins, M. A. Beard, J. D. Gaines, P. A. Ashour, M. Y. Uberoi, R. Braithwaite, B. Whitaker, S. C. Davies, J. N. Travis, S. Hamilton, G. Platts, A. Shandall, A. Sullivan, B. A. Sobeh, M. Matson, M. Fox, A. D. Orme, R. Yusef, W. Doyle, T. Horrocks, M. Hardman, J. Blair, P. H. B. Ellis, P. K. Morris, G. Odurny, A. Vohra, R. Duddy, M. Thompson, M. Loosemore, T. M. L. Belli, A. M. Morgan, R. Adiseshiah, M. Brookes, J. A. S. McCollum, C. N. Ashleigh, R. Aukett, M. Baker, S. Barbe, E. Batson, N. Bell, J. Blundell, J. Boardley, D. Boyes, S. Brown, O. Bryce, J. Carmichael, M. Chance, T. Coleman, J. Cosgrove, C. Curran, G. Dennison, T. Devine, C. Dewhirst, N. Errington, B. Farrell, H. Fisher, C. Fulford, P. Gough, M. Graham, C. Hooper, R. Horne, G. Horrocks, L. Hughes, B. Hutchings, T. Ireland, M. Judge, C. Kelly, L. Kemp, J. Kite, A. Kivela, M. Lapworth, M. Lee, C. Linekar, L. Mahmood, A. March, L. Martin, J. Matharu, N. McGuigen, K. Morris‐Vincent, P. Murray, S. Murtagh, A. Owen, G. Ramoutar, V. Rippin, C. Rowley, J. Sinclair, J. Spencer, S. Taylor, V. Tomlinson, C. Ward, S. Wealleans, V. West, J. White, K. Williams, J. Wilson, L. Grobbee, D. E. Blankensteijn, J. D. Bak, A. A. A. Buth, J. Pattynama, P. M. Verhoeven, E. L. G. van Voorthuisen, A. E. Blankensteijn, J. D. Balm, R. Buth, J. Cuypers, P. W. M. Grobbee, D. E. Prinssen, M. van Sambeek, M. R. H. M. Verhoeven, E. L. G. Baas, A. F. Hunink, M. G. van Engelshoven, J. M. Jacobs, M. J. H. M. de Mol, B. A. J. M. van Bockel, J. H. Balm, R. Reekers, J. Tielbeek, X. Verhoeven, E. L. G. Wisselink, W. Boekema, N. Heuveling, L. M. Sikking, I. Prinssen, M. Balm, R. Blankensteijn, J. D. Buth, J. Cuypers, P. W. M. van Sambeek, M. R. H. M. Verhoeven, E. L. G. de Bruin, J. L. Baas, A. F. Blankensteijn, J. D. Prinssen, M. Buth, J. Tielbeek, A.V. Blankensteijn, J. D. Balm, R. Reekers, J. A. van Sambeek, M. R. H. M. Pattynama, P. Verhoeven, E. L. G. Prins, T. van der Ham, A. C. van der Velden, J. J. I. M. van Sterkenburg, S. M. M. ten Haken, G. B. Bruijninckx, C. M. A. van Overhagen, H. Tutein Nolthenius, R. P. Hendriksz, T. R. Teijink, J. A. W. Odink, H. F. de Smet, A. A. E. A. Vroegindeweij, D. van Loenhout, R. M. M. Rutten, M. J. Hamming, J. F. Lampmann, L. E. H. Bender, M. H. M. Pasmans, H. Vahl, A. C. de Vries, C. Mackaay, A. J. C. van Dortmont, L. M. C. van der Vliet, A. J. Schultze Kool, L. J. Boomsma, J. H. B. van Dop, H. R. de Mol van Otterloo, J. C. A. de Rooij, T. P. W. Smits, T. M. Yilmaz, E. N. Wisselink, W. van den Berg, F. G. Visser, M. J. T. van der Linden, E. Schurink, G. W. H. de Haan, M. Smeets, H. J. Stabel, P. van Elst, F. Poniewierski, J. Vermassen, F. E. G. Lederle, F. A. Freischlag, J. A. Kohler, T. R. Latts, E. Matsumura, J. Padberg, F. T. Kyriakides, T. C. Swanson, K. M. Guarino, P. Peduzzi, P. Antonelli, M. Cushing, C. Davis, E. Durant, L. Joyner, S. Kossack, the late A. Kyriakides, T. C. LeGwin, Mary McBride, V. O'Connor, T. Poulton, J. Stratton, the late S. Zellner, S. Snodgrass, A. J. Thornton, J. Swanson, K. M. Haakenson, C. M. Stroupe, K.T. Jonk, Y. Hallett, J. W. Hertzer, N. Towne, J. Katz, D. A. Karrison, T. Matts, J. P. Marottoli, R. Kasl, S. Mehta, R. Feldman, R. Farrell, W. Allore, H. Perry, E. Niederman, J. Randall, F. Zeman, M. Beckwith, the late D. O'Leary, T. J. Huang, G. D. Latts, E. Bader, M. Ketteler, E. R. Kingsley, D. D. Marek, J. M. Massen, R. J. Matteson, B. D. Pitcher, J. D. Langsfeld, M. Corson, J. D. Goff, J. M. Kasirajan, K. Paap, C. Robertson, D. C. Salam, A. Veeraswamy, R. Milner, R. Kasirajan, K. Guidot, J. Lal, B. K. Busuttil, S. J. Lilly, M. P. Braganza, M. Ellis, K. Patterson, M. A. Jordan, W. D. Whitley, D. Taylor, S. Passman, M. Kerns, D. Inman, C. Poirier, J. Ebaugh, J. Raffetto, J. Chew, D. Lathi, S. Owens, C. Hickson, K. Dosluoglu, H. H. Eschberger, K. Kibbe, M. R. Baraniewski, H. M. Matsumura, J. Endo, M. Busman, A. Meadows, W. Evans, M. Giglia, J. S. El Sayed, H. Reed, A. B. Ruf, M. Ross, S. Jean‐Claude, J. M. Pinault, G. Kang, P. White, N. Eiseman, M. Jones, the late R. Timaran, C. H. Modrall, J. G. Welborn, M. B. Lopez, J. Nguyen, T. Chacko, J. K. Y. Granke, K. Vouyouka, A. G. Olgren, E. Chand, P. Allende, B. Ranella, M. Yales, C. Whitehill, T. A. Krupski, the late W. C. Nehler, M. R. Johnson, S. P. Jones, D. N. Strecker, P. Bhola, M. A. Shortell, C. K. Gray, J. L. Lawson, J. H. McCann, R. Sebastian, M.W. Kistler Tetterton, J. Blackwell, C. Prinzo, P. A. Lee, N. Padberg, F. T. Cerveira, J. J. Lal, B. K. Zickler, R. W. Hauck, K. A. Berceli, S. A. Lee, W. A. Ozaki, C. K. Nelson, P. R. Irwin, A. S. Baum, R. Aulivola, B. Rodriguez, H. Littooy, F. N. Greisler, H. O'Sullivan, M. T. Kougias, P. Lin, P. H. Bush, R. L. Guinn, G. Bechara, C. Cagiannos, C. Pisimisis, G. Barshes, N. Pillack, S. Guillory, B. Cikrit, D. Lalka, S. G. Lemmon, G. Nachreiner, R. Rusomaroff, M. O'Brien, E. Cullen, J. J. Hoballah, J. Sharp, W. J. McCandless, J. L. Beach, V. Minion, D. Schwarcz, T. H. Kimbrough, J. Ashe, L. Rockich, A. Warner‐Carpenter, J. Moursi, M. Eidt, J. F. Brock, S. Bianchi, C. Bishop, V. Gordon, I. L. Fujitani, R. Kubaska, S. M. Behdad, M. Azadegan, R. Ma Agas, C. Zalecki, K. Hoch, J. R. Carr, S. C. Acher, C. Schwarze, M. Tefera, G. Mell, M. Dunlap, B. Rieder, J. Stuart, J. M. Weiman, D. S. Abul‐Khoudoud, O. Garrett, H. E. Walsh, S. M. Wilson, K. L. Seabrook, G. R. Cambria, R. A. Brown, K. R. Lewis, B. D. Framberg, S. Kallio, C. Barke, R. A. Santilli, S. M. d'Audiffret, A. C. Oberle, N. Proebstle, C. Johnson, L. L. Jacobowitz, G. R. Cayne, N. Rockman, C. Adelman, M. Gagne, P. Nalbandian, M. Caropolo, L. J. Pipinos, I. I. Johanning, J. Lynch, T. DeSpiegelaere, H. Purviance, G. Zhou, W. Dalman, R. Lee, J. T. Safadi, B. Coogan, S. M. Wren, S. M. Bahmani, D. D. Maples, D. Thunen, S. Golden, M. A. Mitchell, M. E. Fairman, R. Reinhardt, S. Wilson, M. A. Tzeng, E. Muluk, S. Peterson, N. M. Foster, M. Edwards, J. Moneta, G. L. Landry, G. Taylor, L. Yeager, R. Cannady, E. Treiman, G. Hatton‐Ward, S. Salabsky, the late B. Kansal, N. Owens, E. Estes, M. Forbes, B. A. Sobotta, C. Rapp, J. H. Reilly, L. M. Perez, S. L. Yan, K. Sarkar, R. Dwyer, S. S. Perez, S. Chong, K. Kohler, T. R. Hatsukami, T. S. Glickerman, D. G. Sobel, M. Burdick, T. S. Pedersen, K. Cleary, P. Back, M. Bandyk, D. Johnson, B. Shames, M. Reinhard, R. L. Thomas, S. C. Hunter, G. C. Leon, L. R. Westerband, A. Guerra, R. J. Riveros, M. Mills, J. L. Hughes, J. D. Escalante, A. M. Psalms, S. B. Day, N. N. Macsata, R. Sidawy, A. Weiswasser, J. Arora, S. Jasper, B. J. Dardik, A. Gahtan, V. Muhs, B. E. Sumpio, B. E. Gusberg, R. J. Spector, M. Pollak, J. Aruny, J. Kelly, E. L. Wong, J. Vasilas, P. Joncas, C. Gelabert, H. A. DeVirgillio, C. Rigberg, D. A. Cole, L. Becquemin, J.‐P. Marzelle, J. Becquemin, J.‐P. Sapoval, M. Becquemin, J.‐P. Favre, J.‐P. Watelet, J. Lermusiaux, P. Sapoval, M. Lepage, E. Hemery, F. Dolbeau, G. Hawajry, N. Cunin, P. Harris, P. Stockx, L. Chatellier, G. Mialhe, C. Fiessinger, J.‐N. Pagny, L. Kobeiter, H. Boissier, C. Lacroix, P. Ledru, F. Pinot, J.‐J. Deux, J.‐F. Tzvetkov, B. Duvaldestin, P. Watelet, J. Jourdain, C. David, V. Enouf, D. Ady, N. Krimi, A. Boudjema, N. Jousset, Y. Enon, B. Blin, V. Picquet, J. L'Hoste, P. Thouveny, F. Borie, H. Kowarski, S. Pernes, J.‐M. Auguste, M. Becquemin, J.‐P. Desgranges, P. Allaire, E. Marzelle, J. Kobeiter, H. Meaulle, P.‐Y. Chaix, D. Juliae, P. Fabiani, J. N. Chevalier, P. Combes, M. Seguin, A. Belhomme, D. Sapoval, M. Baque, J. Pellerin, O. Favre, J. P. Barral, X. Veyret, C. Watelet, J. Peillon, C. Plissonier, D. Thomas, P. Clavier, E. Lermusiaux, P. Martinez, R. Bleuet, F. C, Dupreix Verhoye, J. P. Langanay, T. Heautot, J. F. Koussa, M. Haulon, S. Halna, P. Destrieux, L. Lions, C. Wiloteaux, S. Beregi, J. P. Bergeron, P. Pinot, J.‐J. Patra, P. Costargent, A. Chaillou, P. D'Alicourt, A. Goueffic, Y. Cheysson, E. Parrot, A. Garance, P. Demon, A. Tyazi, A. Pillet, J.‐C. Lescalie, F. Tilly, G. Steinmetz, E. Favier, C. Brenot, R. Krause, D. Cercueil, J. P. Vahdat, O. Sauer, M. Soula, P. Querian, A. Garcia, O. Levade, M. Colombier, D. Cardon, J.‐M. Joyeux, A. Borrelly, P. Dogas, G. Magnan, P.‐É. Branchereau, A. Bartoli, J.‐M. Hassen‐Khodja, R. Batt, M. Planchard, P.‐F. Bouillanne, P.‐J. Haudebourg, P. Bayne, J. Gouny, P. Badra, A. Braesco, J. Nonent, M. Lucas, A. Cardon, A. Kerdiles, Y. Rolland, Y. Kassab, M. Brillu, C. Goubault, F. Tailboux, L. Darrieux, H. Briand, O. Maillard, J.‐C. Varty, K. Cousins, C. Br J Surg Systematic Reviews BACKGROUND: The erosion of the early mortality advantage of elective endovascular aneurysm repair (EVAR) compared with open repair of abdominal aortic aneurysm remains without a satisfactory explanation. METHODS: An individual‐patient data meta‐analysis of four multicentre randomized trials of EVAR versus open repair was conducted to a prespecified analysis plan, reporting on mortality, aneurysm‐related mortality and reintervention. RESULTS: The analysis included 2783 patients, with 14 245 person‐years of follow‐up (median 5·5 years). Early (0–6 months after randomization) mortality was lower in the EVAR groups (46 of 1393 versus 73 of 1390 deaths; pooled hazard ratio 0·61, 95 per cent c.i. 0·42 to 0·89; P = 0·010), primarily because 30‐day operative mortality was lower in the EVAR groups (16 deaths versus 40 for open repair; pooled odds ratio 0·40, 95 per cent c.i. 0·22 to 0·74). Later (within 3 years) the survival curves converged, remaining converged to 8 years. Beyond 3 years, aneurysm‐related mortality was significantly higher in the EVAR groups (19 deaths versus 3 for open repair; pooled hazard ratio 5·16, 1·49 to 17·89; P = 0·010). Patients with moderate renal dysfunction or previous coronary artery disease had no early survival advantage under EVAR. Those with peripheral artery disease had lower mortality under open repair (39 deaths versus 62 for EVAR; P = 0·022) in the period from 6 months to 4 years after randomization. CONCLUSION: The early survival advantage in the EVAR group, and its subsequent erosion, were confirmed. Over 5 years, patients of marginal fitness had no early survival advantage from EVAR compared with open repair. Aneurysm‐related mortality and patients with low ankle : brachial pressure index contributed to the erosion of the early survival advantage for the EVAR group. Trial registration numbers: EVAR‐1, ISRCTN55703451; DREAM (Dutch Randomized Endovascular Aneurysm Management), NCT00421330; ACE (Anévrysme de l'aorte abdominale, Chirurgie versus Endoprothèse), NCT00224718; OVER (Open Versus Endovascular Repair Trial for Abdominal Aortic Aneurysms), NCT00094575. John Wiley & Sons, Ltd 2017-02-03 2017-02 /pmc/articles/PMC5299468/ /pubmed/28160528 http://dx.doi.org/10.1002/bjs.10430 Text en © 2017 The Authors. BJS published by John Wiley & Sons Ltd on behalf of BJS Society Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle	Systematic Reviews Powell, J. T. Sweeting, M. J. Ulug, P. Blankensteijn, J. D. Lederle, F. A. Becquemin, J.‐P. Greenhalgh, R. M. Greenhalgh, R. M. Beard, J. D. Buxton, M. J. Brown, L. C. Harris, P. L. Powell, J. T. Rose, J. D. G. Russell, I. T. Sculpher, M. J. Thompson, S. G. Lilford, R.J. Bell, P. R. F. Greenhalgh, R. M. Whitaker, S.C. Poole‐Wilson, the late P.A. Ruckley, C. V. Campbell, W. B. Dean, M. R. E. Ruttley, M. S. T. Coles, E. C. Powell, J. T. Halliday, A. Gibbs, S. J. Brown, L. C. Epstein, D. Sculpher, M. J. Thompson, S. G. Hannon, R. J. Johnston, L. Bradbury, A. W. Henderson, M. J. Parvin, S. D. Shepherd, D. F. C. Greenhalgh, R. M. Mitchell, A. W. Edwards, P. R. Abbott, G. T. Higman, D. J. Vohra, A. Ashley, S. Robottom, C. Wyatt, M. G. Rose, J. D. G. Byrne, D. Edwards, R. Leiberman, D. P. McCarter, D. H. Taylor, P. R. Reidy, J. F. Wilkinson, A. R. Ettles, D. F. Clason, A. E. Leen, G. L. S. Wilson, N. V. Downes, M. Walker, S. R. Lavelle, J. M. Gough, M. J. McPherson, S. Scott, D. J. A. Kessell, D. O. Naylor, R. Sayers, R. Fishwick, N. G. Harris, P. L. Gould, D. A. Walker, M. G. Chalmers, N. C. Garnham, A. Collins, M. A. Beard, J. D. Gaines, P. A. Ashour, M. Y. Uberoi, R. Braithwaite, B. Whitaker, S. C. Davies, J. N. Travis, S. Hamilton, G. Platts, A. Shandall, A. Sullivan, B. A. Sobeh, M. Matson, M. Fox, A. D. Orme, R. Yusef, W. Doyle, T. Horrocks, M. Hardman, J. Blair, P. H. B. Ellis, P. K. Morris, G. Odurny, A. Vohra, R. Duddy, M. Thompson, M. Loosemore, T. M. L. Belli, A. M. Morgan, R. Adiseshiah, M. Brookes, J. A. S. McCollum, C. N. Ashleigh, R. Aukett, M. Baker, S. Barbe, E. Batson, N. Bell, J. Blundell, J. Boardley, D. Boyes, S. Brown, O. Bryce, J. Carmichael, M. Chance, T. Coleman, J. Cosgrove, C. Curran, G. Dennison, T. Devine, C. Dewhirst, N. Errington, B. Farrell, H. Fisher, C. Fulford, P. Gough, M. Graham, C. Hooper, R. Horne, G. Horrocks, L. Hughes, B. Hutchings, T. Ireland, M. Judge, C. Kelly, L. Kemp, J. Kite, A. Kivela, M. Lapworth, M. Lee, C. Linekar, L. Mahmood, A. March, L. Martin, J. Matharu, N. McGuigen, K. Morris‐Vincent, P. Murray, S. Murtagh, A. Owen, G. Ramoutar, V. Rippin, C. Rowley, J. Sinclair, J. Spencer, S. Taylor, V. Tomlinson, C. Ward, S. Wealleans, V. West, J. White, K. Williams, J. Wilson, L. Grobbee, D. E. Blankensteijn, J. D. Bak, A. A. A. Buth, J. Pattynama, P. M. Verhoeven, E. L. G. van Voorthuisen, A. E. Blankensteijn, J. D. Balm, R. Buth, J. Cuypers, P. W. M. Grobbee, D. E. Prinssen, M. van Sambeek, M. R. H. M. Verhoeven, E. L. G. Baas, A. F. Hunink, M. G. van Engelshoven, J. M. Jacobs, M. J. H. M. de Mol, B. A. J. M. van Bockel, J. H. Balm, R. Reekers, J. Tielbeek, X. Verhoeven, E. L. G. Wisselink, W. Boekema, N. Heuveling, L. M. Sikking, I. Prinssen, M. Balm, R. Blankensteijn, J. D. Buth, J. Cuypers, P. W. M. van Sambeek, M. R. H. M. Verhoeven, E. L. G. de Bruin, J. L. Baas, A. F. Blankensteijn, J. D. Prinssen, M. Buth, J. Tielbeek, A.V. Blankensteijn, J. D. Balm, R. Reekers, J. A. van Sambeek, M. R. H. M. Pattynama, P. Verhoeven, E. L. G. Prins, T. van der Ham, A. C. van der Velden, J. J. I. M. van Sterkenburg, S. M. M. ten Haken, G. B. Bruijninckx, C. M. A. van Overhagen, H. Tutein Nolthenius, R. P. Hendriksz, T. R. Teijink, J. A. W. Odink, H. F. de Smet, A. A. E. A. Vroegindeweij, D. van Loenhout, R. M. M. Rutten, M. J. Hamming, J. F. Lampmann, L. E. H. Bender, M. H. M. Pasmans, H. Vahl, A. C. de Vries, C. Mackaay, A. J. C. van Dortmont, L. M. C. van der Vliet, A. J. Schultze Kool, L. J. Boomsma, J. H. B. van Dop, H. R. de Mol van Otterloo, J. C. A. de Rooij, T. P. W. Smits, T. M. Yilmaz, E. N. Wisselink, W. van den Berg, F. G. Visser, M. J. T. van der Linden, E. Schurink, G. W. H. de Haan, M. Smeets, H. J. Stabel, P. van Elst, F. Poniewierski, J. Vermassen, F. E. G. Lederle, F. A. Freischlag, J. A. Kohler, T. R. Latts, E. Matsumura, J. Padberg, F. T. Kyriakides, T. C. Swanson, K. M. Guarino, P. Peduzzi, P. Antonelli, M. Cushing, C. Davis, E. Durant, L. Joyner, S. Kossack, the late A. Kyriakides, T. C. LeGwin, Mary McBride, V. O'Connor, T. Poulton, J. Stratton, the late S. Zellner, S. Snodgrass, A. J. Thornton, J. Swanson, K. M. Haakenson, C. M. Stroupe, K.T. Jonk, Y. Hallett, J. W. Hertzer, N. Towne, J. Katz, D. A. Karrison, T. Matts, J. P. Marottoli, R. Kasl, S. Mehta, R. Feldman, R. Farrell, W. Allore, H. Perry, E. Niederman, J. Randall, F. Zeman, M. Beckwith, the late D. O'Leary, T. J. Huang, G. D. Latts, E. Bader, M. Ketteler, E. R. Kingsley, D. D. Marek, J. M. Massen, R. J. Matteson, B. D. Pitcher, J. D. Langsfeld, M. Corson, J. D. Goff, J. M. Kasirajan, K. Paap, C. Robertson, D. C. Salam, A. Veeraswamy, R. Milner, R. Kasirajan, K. Guidot, J. Lal, B. K. Busuttil, S. J. Lilly, M. P. Braganza, M. Ellis, K. Patterson, M. A. Jordan, W. D. Whitley, D. Taylor, S. Passman, M. Kerns, D. Inman, C. Poirier, J. Ebaugh, J. Raffetto, J. Chew, D. Lathi, S. Owens, C. Hickson, K. Dosluoglu, H. H. Eschberger, K. Kibbe, M. R. Baraniewski, H. M. Matsumura, J. Endo, M. Busman, A. Meadows, W. Evans, M. Giglia, J. S. El Sayed, H. Reed, A. B. Ruf, M. Ross, S. Jean‐Claude, J. M. Pinault, G. Kang, P. White, N. Eiseman, M. Jones, the late R. Timaran, C. H. Modrall, J. G. Welborn, M. B. Lopez, J. Nguyen, T. Chacko, J. K. Y. Granke, K. Vouyouka, A. G. Olgren, E. Chand, P. Allende, B. Ranella, M. Yales, C. Whitehill, T. A. Krupski, the late W. C. Nehler, M. R. Johnson, S. P. Jones, D. N. Strecker, P. Bhola, M. A. Shortell, C. K. Gray, J. L. Lawson, J. H. McCann, R. Sebastian, M.W. Kistler Tetterton, J. Blackwell, C. Prinzo, P. A. Lee, N. Padberg, F. T. Cerveira, J. J. Lal, B. K. Zickler, R. W. Hauck, K. A. Berceli, S. A. Lee, W. A. Ozaki, C. K. Nelson, P. R. Irwin, A. S. Baum, R. Aulivola, B. Rodriguez, H. Littooy, F. N. Greisler, H. O'Sullivan, M. T. Kougias, P. Lin, P. H. Bush, R. L. Guinn, G. Bechara, C. Cagiannos, C. Pisimisis, G. Barshes, N. Pillack, S. Guillory, B. Cikrit, D. Lalka, S. G. Lemmon, G. 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Chaillou, P. D'Alicourt, A. Goueffic, Y. Cheysson, E. Parrot, A. Garance, P. Demon, A. Tyazi, A. Pillet, J.‐C. Lescalie, F. Tilly, G. Steinmetz, E. Favier, C. Brenot, R. Krause, D. Cercueil, J. P. Vahdat, O. Sauer, M. Soula, P. Querian, A. Garcia, O. Levade, M. Colombier, D. Cardon, J.‐M. Joyeux, A. Borrelly, P. Dogas, G. Magnan, P.‐É. Branchereau, A. Bartoli, J.‐M. Hassen‐Khodja, R. Batt, M. Planchard, P.‐F. Bouillanne, P.‐J. Haudebourg, P. Bayne, J. Gouny, P. Badra, A. Braesco, J. Nonent, M. Lucas, A. Cardon, A. Kerdiles, Y. Rolland, Y. Kassab, M. Brillu, C. Goubault, F. Tailboux, L. Darrieux, H. Briand, O. Maillard, J.‐C. Varty, K. Cousins, C. Meta‐analysis of individual‐patient data from EVAR‐1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years
title	Meta‐analysis of individual‐patient data from EVAR‐1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years
title_full	Meta‐analysis of individual‐patient data from EVAR‐1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years
title_fullStr	Meta‐analysis of individual‐patient data from EVAR‐1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years
title_full_unstemmed	Meta‐analysis of individual‐patient data from EVAR‐1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years
title_short	Meta‐analysis of individual‐patient data from EVAR‐1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years
title_sort	meta‐analysis of individual‐patient data from evar‐1, dream, over and ace trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years
topic	Systematic Reviews
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299468/ https://www.ncbi.nlm.nih.gov/pubmed/28160528 http://dx.doi.org/10.1002/bjs.10430
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metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT belhommed metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT sapovalm metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT baquej metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT pellerino metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT favrejp metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT barralx metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT veyretc metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT wateletj metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT peillonc metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT plissonierd metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT thomasp metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT claviere 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metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT heautotjf metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT koussam metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT haulons metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT halnap metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT destrieuxl metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT lionsc metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT wiloteauxs metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT beregijp metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT bergeronp metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT pinotjj metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT patrap metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT costargenta metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT chailloup metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT dalicourta metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT gouefficy metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT cheyssone metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT parrota metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT garancep metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT demona metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT tyazia metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT pilletjc metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT lescalief metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT tillyg metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT steinmetze metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT favierc metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT brenotr metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT kraused metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT cercueiljp metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT vahdato metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT sauerm metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT soulap metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT queriana metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT garciao metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT levadem metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT colombierd metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT cardonjm metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT joyeuxa metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT borrellyp metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT dogasg metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT magnanpe metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT branchereaua metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT bartolijm metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT hassenkhodjar metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT battm metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT planchardpf metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT bouillannepj metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT haudebourgp metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT baynej metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT gounyp metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT badraa metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT braescoj metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT nonentm metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT lucasa metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT cardona metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT kerdilesy metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT rollandy metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT kassabm metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT brilluc metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT goubaultf metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT tailbouxl metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT darrieuxh metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT briando metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT maillardjc metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT vartyk metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years AT cousinsc metaanalysisofindividualpatientdatafromevar1dreamoverandacetrialscomparingoutcomesofendovascularoropenrepairforabdominalaorticaneurysmover5years

Meta‐analysis of individual‐patient data from EVAR‐1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years

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