Gene variation in IL-7 receptor (IL-7R)α affects IL-7R response in CD4+ T cells in HIV-infected individuals

Optimal CD4+ T cell recovery after initiating combination antiretroviral treatment (cART) in HIV infection reduces risk of morbidity and mortality. T-allele homozygosity (‘TT’) in the single nucleotide polymorphism, rs6897932(C/T), in the IL-7 receptor α (IL-7RA) is associated with faster CD4+ T cel...

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Detalles Bibliográficos
Autores principales: Hartling, Hans Jakob, Ryder, Lars P., Ullum, Henrik, Ødum, Niels, Nielsen, Susanne Dam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299473/
https://www.ncbi.nlm.nih.gov/pubmed/28181541
http://dx.doi.org/10.1038/srep42036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299473/
https://www.ncbi.nlm.nih.gov/pubmed/28181541
http://dx.doi.org/10.1038/srep42036

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