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Gene variation in IL-7 receptor (IL-7R)α affects IL-7R response in CD4+ T cells in HIV-infected individuals
Optimal CD4+ T cell recovery after initiating combination antiretroviral treatment (cART) in HIV infection reduces risk of morbidity and mortality. T-allele homozygosity (‘TT’) in the single nucleotide polymorphism, rs6897932(C/T), in the IL-7 receptor α (IL-7RA) is associated with faster CD4+ T cel...
Autores principales: | Hartling, Hans Jakob, Ryder, Lars P., Ullum, Henrik, Ødum, Niels, Nielsen, Susanne Dam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299473/ https://www.ncbi.nlm.nih.gov/pubmed/28181541 http://dx.doi.org/10.1038/srep42036 |
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