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Solubilization of Membrane Proteins into Functional Lipid‐Bilayer Nanodiscs Using a Diisobutylene/Maleic Acid Copolymer

Once removed from their natural environment, membrane proteins depend on membrane‐mimetic systems to retain their native structures and functions. To this end, lipid‐bilayer nanodiscs that are bounded by scaffold proteins or amphiphilic polymers such as styrene/maleic acid (SMA) copolymers have been...

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Detalles Bibliográficos
Autores principales: Oluwole, Abraham Olusegun, Danielczak, Bartholomäus, Meister, Annette, Babalola, Jonathan Oyebamiji, Vargas, Carolyn, Keller, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299484/
https://www.ncbi.nlm.nih.gov/pubmed/28079955
http://dx.doi.org/10.1002/anie.201610778